Metastasis, when cancer cells leave the breast and spread to other sites in the body, is the major cause of mortality from breast cancer. The brain is one of the most common organs breast cancer invades, occurring in more than one third of patients with advanced breast cancer, up to 300,000 patients a year. The prognosis of cancer patients who develop brain metastasis is poor, with only 20 percent of patients surviving at one year.
For Dr. Priscilla Brastianos, a BCRF investigator since 2017, this cause hits close to home. Both her mother and grandmother died of metastatic breast cancer. That’s why she has dedicated her career to better understanding brain metastasis. As the Director of the Central Nervous System Metastasis Program & Assistant Professor of Medicine at Harvard Medical School and Massachusetts General Hospital, her research focuses on understanding the mechanisms driving metastatic disease to the brain. She is currently conducting studies to characterize the genetic and molecular profiles of brain metastasis compared to primary breast cancer with the goal of identifying potential targets for therapy and strategies to improve response to existing therapies.
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Improving Breast Cancer Radiation Treatments with Dr. Rachel Jimenez
The Effects of a High-Fiber Diet in Early-Stage Breast Cancer with Dr. Laura Esserman
BCRF 2023 New York City Symposium
Investigating Novel Biomarkers for Personalized Treatments with Dr. Roisin Connolly
Reflecting on Thirty Years of Progress with Dr. Larry Norton
The Progress and Future of Breast Cancer Vaccines with Dr. Nora Disis
The Future of Breast Cancer Risk Prediction with Dr. Regina Barzilay
Lowering Barriers to Breast Cancer Genetic Testing with Dr. Susan Domchek
Studying Breast Cancer Risk in Asian American Communities with Dr. Scarlett Gomez
Bridging the Gap Between the Lab and Patient Care with Dr. Ian Krop
Understanding and Targeting Triple-Negative Breast Cancer with Dr. Jill Bargonetti
Exploring Social Determinants of Health in Breast Cancer Care with Dr. Sonya Reid
BCRF Investigators Discuss the Latest in Breast Cancer Research at 2022 Symposium
Finding and Targeting “Sleeping” Cancer Cells with Dr. Angela DeMichele
Investigating What Drives Recurrence and Metastasis with Dr. Christina Curtis
The Impact of Chemotherapy on Accelerated Aging in Elderly Patients with Dr. Hyman Muss
Advancing Breast Cancer Immunotherapy and Decoding Treatment Resistance with Dr. Hope Rugo
Improving Breast Cancer Care and Narrowing the Health Disparities Gap with Dr. Dawn Hershman
The Urgent Need for Triple-Negative Breast Cancer Breakthroughs with Dr. Elisa Port
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