HOUR 2
Mitochondria and Magnesium - A Cellular Energy Essential- Carolyn Dean MD ND
Magnesium’s role in mitochondrial function is known in scientific circles yet many clinicians have not gotten up to speed with its use and still think of it as a laxative.
Commonly known as the powerhouses of the cell the major role of mitochondria is to produce energy (ATP) in the Krebs cycle, usi...
HOUR 2
Mitochondria and Magnesium - A Cellular Energy Essential- Carolyn Dean MD ND
Magnesium’s role in mitochondrial function is known in scientific circles yet many clinicians have not gotten up to speed with its use and still think of it as a laxative.
Commonly known as the powerhouses of the cell the major role of mitochondria is to produce energy (ATP) in the Krebs cycle, using magnesium in 6 of its 8 steps. But its other roles include:
- Calcium homeostasis (which requires Mg)
- Apoptosis: cell death (triggered by Mg deficiency affecting telomerase)
- Free radical species generation (hastened by Mg deficiency)
- Radical species scavenging (assisted by Mg)
- Steroid biosynthesis (Mg aids in production)
- Orchestrate metabolism (Mg helps digest protein, fats, carbs)
Our bodies make energy by breaking down food into glucose that then creates an electrical charge that is sent across the mitochondrial double membranes, making the inside of the mitochondria negative and the space between the mitochondria membranes positive. This charge potential difference is essentially a battery. The battery changes ADP to the energy molecule ATP.
When the mitochondria fail to perform this process properly, mitochondrial disease results. However, there is no single test that can diagnose mitochondrial disease but apparently, researchers have identified nearly 300 different known genetic causes. Again, this amplifies the difference between the science of the mitochondria that focuses on genetic mutations of mitochondria and treating mitochondrial dysfunction.
An NIH report on “Dietary Supplements for Primary Mitochondrial Disorders” did not mention magnesium being used as a treatment.
The first mitochondrial DNA disease was identified nearly 30 years ago, leading to an entirely new medical field. Many people whose mitochondria fail to produce sufficient energy have neurologic problems. These can include strokes, seizures, and headaches such as migraines – all worsened by magnesium deficiency. Any part of the nervous system can be affected, including the peripheral and the autonomic nervous systems. Any organ that depends on energy to function—ie, all of them—can be affected. Common systems affected include muscles, kidneys, liver, vision, hearing, the hormonal system, and blood.
Exercise is very important because it can increase the number of mitochondria and can shift the levels of errors in the mitochondrial DNA and increase the function of those mitochondria. When you exercise, your muscles require more energy in the form of ATP that is made in the mitochondria. And remember, 6 of the 8 steps in the Krebs cycle require magnesium to make ATP. Oxygen is required during exercise, respiratory rate and heart rate increase. Both require magnesium. Without sufficient oxygen, lactic acid will form instead and magnesium is necessary to reduce lactic acid. Then there is the fact that it’s the tiny tears from the damage that exercise causes in your muscles that makes them grow bigger and stronger as they heal. Any type of inflammation, pain, or swelling in the muscles requires magnesium in order to heal.
When it comes to nutrition, magnesium saturation and specific vitamins are very important to the functioning of the mitochondrial electron transport chain and all of the enzymes within it. The nutrients that are recommended are B vitamins, antioxidants such as vitamin A and vitamin C, and magnesium.
Tonight on our internet based radio show, we’ll be talking with Dr. Carolyn Dean about Magnesium and Mitochondria along with a wide range of health topics and safe solutions. You will love hearing the beneficial interactions with our callers and hosts alike including the body/mind connection, identifying the ‘conflict’ in the ‘conflict basis’ of disease and much more!!
About Dr. Carolyn Dean
Dr Carolyn Dean MD ND has been featured on national media for over 30 years offering practical strategies to improve health, vitality, and well-being the natural way. As a medical doctor, naturopath, certified clinical nutritionist and master of many modalities including acupuncture and homeopathy, Dr. Carolyn Dean MD ND has authored over 33 books and 100 publications including The Magnesium Miracle, 3rd Edition, Hormone Balance, Future Health Now Encyclopedia and Heart Health. Please note that the information and opinions expressed on these broadcasts are not designed to constitute advice or recommendations as to any disease, ailment, or physical condition. You should not act or rely upon any information contained in these broadcasts without seeking the advice of your personal physician. If you have any questions about the information or opinions expressed during these broadcasts, please contact your doctor.
Disclosure: Dr. Dean does have a financial interest in the sale of all the Completement Formulas.
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