The Gary Null Show - 11.15.22

VIDEOS:

1. Niall Ferguson – Woke Totalitarianism (0:19 to 18:14)
2. How Ukraine – Not Russia – Floods Social Media With War Propaganda (0:00 to 1:20)
3. Here’s why no one trusts CNN (3:35)
4. The Green New Deal’s Bad Science (8:14)
5. JUST IN: Matt Gaetz Says Kevin McCarthy Could Ask Democrats To Help Make Him Speaker Forbes Breaking News 1.35M subscribers Subscribe (5:19)
6. Neil Oliver asks why we should be expected to sweep Covid hysteria under the rug? (0:36 to 5:32)
7. Jimmy Dore – Tim Robbins Apologizes To Unvaccinated For Being Wrong On Covid Policy (0:00 to 9:13)

Grape Powder Could Extend Lifespan by 4-5 Years

Long Island University, November 3, 2022

In a study the authors called “remarkable,” researchers found that giving grape powder to mice reduced the risk of non-alcoholic fatty liver disease and extended lifespan.

To see if grape powder could modulate the harmful effects of a high-fat diet, researchers fed mice a typical Western (high-fat) diet. Half then received 5% standardized grape powder while the other half didn’t.

Compared to mice not fed the grape powder, the mice given grape powder saw beneficial increases in antioxidant genes, reductions in fatty liver, and extended lifespans.

The lead author estimated that when translated to humans, the extended lifespan would correspond to an additional 4-5 years in the life of a human.

The grape powder used in this study was composed of fresh red, green and black grapes that were freeze-dried to retain their bioactive compounds.

The researchers concluded: “These results suggest the potential of dietary grapes to modulate hepatic gene expression, prevent oxidative damage, induce fatty acid metabolism, ameliorate NAFLD (non-alcoholic fatty liver disease), and increase longevity when co-administered with a high-fat diet.”

Study: Neuroprotective Effect of Virgin Coconut Oil Helps Relieve ALS  Katholieke University (Belgium), November 6, 2022  
An animal study looked into the potential of coconut oil for preventing or reducing ALS symptoms.
Coconut oil has already demonstrated safe efficacy for treating Alzheimer’s disease symptoms, which is also a neurodegenerative disease for which mainstream medicine has no answer. 1H-magnetic resonance spectroscopy is ideal for ALS treatment diagnostics and research. It is used for many animal and human studies to isolate minute molecular changes in brain and nervous system studies without having to procure tissue and blood samples. Thus, it is non-invasive.[The study results] revealed that the coconut oil supplementation together with the regular diet delayed disease symptoms, enhanced motor performance, and prolonged survival in the SOD1G93A mouse model. Furthermore, MRS data showed stable metabolic profile at day 120 in the coconut oil diet group compared to the group receiving a standard diet without coconut oil supplementation.  In addition, a positive correlation between survival and the neuronal marker NAA was found. … this is the first study that reports metabolic changes in the brainstem using in vivo MRS and effects of coconut oil supplementation as a prophylactic treatment in SOD1G93A mice.One of the major metabolites NAA (N-acetylaspartate), has been observed as an integral part of neuron loss, which is a major factor of onset ALS when it is diminished from the central nervous system.  NAA reduction was greater in the non-coconut oil fed group of rats, indicating those on coconut oil were experiencing less neurodegeneration and neuronal destruction. Aerobic activity can reduce the risk of metastatic cancer by 72%

Tel Aviv University (Israel), November 14, 2022

A new study at Tel Aviv University found that aerobic exercise can reduce the risk of metastatic cancer by 72%. According to the researchers, intensity aerobic exercise increases the glucose (sugar) consumption of internal organs, thereby reducing the availability of energy to the tumor.

The study was led by two researchers from TAU’s Sackler Faculty of Medicine.

Prof. Levy and Dr. Gepner said, “Studies have demonstrated that physical exercise reduces the risk for some types of cancer by up to 35%. This positive effect is similar to the impact of exercise on other conditions, such as heart disease and diabetes. In this study we added new insight, showing that high-intensity aerobic exercise, which derives its energy from sugar, can reduce the risk of metastatic cancer by as much as 72%. If so far the general message to the public has been ‘be active, be healthy,’ now we can explain how aerobic activity can maximize the prevention of the most aggressive and metastatic types of cancer.”

The study combined an animal model in which mice were trained under a strict exercise regimen, with data from healthy human volunteers examined before and after running. The human data, obtained from an epidemiological study that monitored 3,000 individuals for about 20 years, indicated 72% less metastatic cancer in participants who reported regular aerobic activity at high intensity, compared to those who did not engage in physical exercise.

They found that aerobic activity significantly reduced the development of metastatic tumors in the lymph nodes, lungs, and liver. The researchers hypothesized that in both humans and model animals, this favorable outcome is related to the enhanced rate of glucose consumption induced by exercise.

Prof. Levy stated, “Our study is the first to investigate the impact of exercise on the internal organs in which metastases usually develop, like the lungs, liver, and lymph nodes.

“Consequently, if cancer develops, the fierce competition over glucose reduces the availability of energy that is critical to metastasis. Moreover, when a person exercises regularly, this condition becomes permanent: the tissues of internal organs change and become similar to muscle tissue. We all know that sports and physical exercise are good for our health. Our study, examining the internal organs, discovered that exercise changes the whole body, so that the cancer cannot spread, and the primary tumor also shrinks in size.”

Dr. Gepner adds, “Our results indicate that unlike fat-burning exercise, which is relatively moderate, it is a high-intensity aerobic activity that helps in cancer prevention. If the optimal intensity range for burning fat is 65–70% of the maximum pulse rate, sugar burning requires 80–85%—even if only for brief intervals. For example: a one-minute sprint followed by walking, then another sprint. 

Vegan diet best for weight loss even with carbohydrate consumption, study finds

University of South Carolina, November 6, 2022

The month of November often brings about a sense of dread at the thought of food filled holiday parties and gatherings, but those who consume a plant based diet have little need for concern. A newstudy by the University of South Carolina confirms one big draw of saying no to all animal products: the ability to shed weight faster than those who consume a diet that contains meat and dairy. 

The study compared the amount of weight lost by those on vegan diets to those on a mostly plant-based diet, and those eating an omnivorous diet with a mix of animal products and plant based foods. At the end of six months, individuals on the vegan diet lost more weight than the other two groups by an average of 4.3%, or 16.5 pounds.

The study followed participants who were randomly assigned to one of five diets on the dietary spectrum: vegan which excludes all animal products, semi-vegetarian with occasional meat intake; pesco-vegetarian which excludes all meat except seafood; vegetarian which excludes all meat and seafood but includes animal products, and omnivorous, which excludes no foods.

Participants followed their assigned dietary restrictions for six months, with all groups except the omnivorous participating in weekly group meetings. Those who stuck to the vegan diet showed the greatest weight loss at the two and six month marks.

The lead authornotes that the diet consumed by vegan participants was high in carbohydrates that rate low on the glycemic index. “We’ve gotten somewhat carb-phobic here in the U.S. when it comes to weight loss. This study might help alleviate the fears of people who enjoy pasta, rice, and other grains but want to lose weight,” she said.

Weight loss was not the only positive outcome for participants in the strictly vegan group. They also showed the greatest amount of decrease in their fat and saturated fat levels at the two and six month checks, had lower BMIs, and improved macro nutrients more than other diets. Eschewing all animal products appears to be key for these positive results. 

Uterine fibroid growth activated by chemicals found in everyday products

Northwestern University, November 14, 2022

For the first time, scientists at Northwestern Medicine have demonstrated a causal link between environmental phthalates (toxic chemicals found in everyday consumer products) and the increased growth of uterine fibroids, the most common tumors among women.

Manufacturers use environmental phthalates in numerous industrial and consumer products, and they’ve also been detected in medical supplies and food. Although they are known to be toxic, they are currently unbanned in the U.S. 

“These toxic pollutants are everywhere, including food packaging, hair and makeup products, and more, and their usage is not banned,” said corresponding study author Dr. Serdar Bulun, chair of the department of obstetrics and gynecology at Northwestern University Feinberg School of Medicine and a Northwestern Medicine physician. “These are more than simply environmental pollutants. They can cause specific harm to human tissues.”

Up to 80% of all women may develop a fibroid tumor during their lifetime, Bulun said. One-quarter of these women become symptomatic with excessive and uncontrolled uterine bleeding, anemia, miscarriages, infertility and large abdominal tumors necessitating technically difficult surgeries.

The new study found women with a high exposure to certain phthalates such as DEHP (used as a plasticizer to increase the durability of products such as shower curtains, car upholstery, lunchboxes, shoes and more) and its metabolites have a high risk for having a symptomatic fibroid.

The scientists discovered exposure to DEHP may activate a hormonal pathway that activates an environmentally responsive receptor (AHR) to bind to DNA and cause increased growth of fibroid tumors.

Immune cells mistake heart attacks for viral infections

University of California San Diego and Harvard University, November 12, 2022 

A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks. The research could lead to new therapeutic strategies for heart disease.

The team, which also includes researchers from the Center for Systems Biology at Massachusetts General Hospital (MGH), Brigham and Women’s Hospital, Harvard Medical School, and the University of Massachusetts, presents the findings in Nature Medicine. Ischemic heart disease is the most common cause of death in the world and it begins with a heart attack. During this process, heart cells die, prompting immune cells to enter the dead tissue, clear debris and orchestrate stabilization of the heart wall.

But what is it about dying cells in the heart that stimulates the immune system? To answer this, researchers looked deep inside thousands of individual cardiac immune cells and mapped their individual transcriptomes using a method called single cell RNA-Seq. This led to the discovery that after a heart attack, DNA from dying cells masquerades as a virus and activates an ancient antiviral program called the type I interferon response in specialized immune cells. The researchers named these “interferon inducible cells (IFNICs).”

When investigators blocked the interferon response, either genetically or with a neutralizing antibody given after the heart attack, there was less inflammation, less heart dysfunction, and improved survival. Specifically, blocking antiviral responses in mice improved survival from 60 percent to over 95 percent. These findings reveal a new potential therapeutic opportunity to prevent heart attacks from progressing to heart failure in patients.

“We are interested to learn whether interferons contribute to adverse cardiovascular outcomes after heart attacks in humans,” said King, who did most of the work on the study while he was a cardiology fellow at Brigham and Women’s Hospital and at the Center for Systems Biology at MGH in Boston.

Investigators found that surprisingly, the antiviral interferon response is also turned on after a heart attack despite the absence of any infection. Their results point to dying cell DNA as the cause of this confusion because the immune system interprets it as the molecular signature of a virus.

Surprisingly, the immune cells participating in the interferon response were a previously unrecognized subset of cardiac macrophages. These cells could not be identified by conventional flow sorting because unique markers on the cell surface were not known. By using single cell RNA Seq, an emerging technique that combines microfluidic nanoliter droplet reactors with single cell barcoding and next generation sequencing, the researchers were able to examine expression of every gene in over 4,000 cardiac immune cells and found the specialized IFNIC population of responsible cells.