Making the FNA Count
Author: Jeffery Rinker
The hospital at Sanford Bemidji Medical Center has 119 beds and performs an average of 150 FNAs each year. Our histologists do both histology and cytology, with FNAs comprising the majority of our cytology. Since 2020, our non-diagnostic rates on FNA samples have fluctuated. In 2022, our rate was as high as 28%. Compared to the non-diagnostic rate of 10% outlined in The Bethesda System for Reporting Thyroid Cytopathology, our results were over two times the accepted rate. To bring non-diagnostic rates down at our facility, a look at processing from beginning to end.
Radiology was the first place to start an overview of the process. During observation, we discovered that multiple passes of the needle contributed the bloodier samples, which affected the specimens processed later. To counter this, we reduced the number of smears and increased the amount of specimen deposited into CytoLyt (ThinPrep).
Next, the cytology department process was examined. During this examination, it was discovered the CytoLyt (Thinprep) specimen was not being processed because of lack of specimen. When it was processed the slides were being dried to long leading to artifact on the slide. By increasing the sample size in radiology and using a slide dryer to regulate the drying, the lab was able to produce a more consistent result.
Following these changes, the lab projected to meet or exceed the goal of less than 10% non-diagnostic slide results by the end of 2023.
P-23 Highly Sensitive Rb Mono Anti-PD-L1 Clone OR-5E3 And OR-5H8 Antibodies For IHC Screen of NSCLC, Bladder Cancer, & Melanoma
P-06 Immunofluorescent Versus IHC Assessment of Mitotic Index for Ki-67 and Phosphohistone-3 (pHH3) in Breast Carcinoma
P-41: SOX-10, MART-1/Melan A, and HMB-45: A Comparison Study of Useful IHC Melanoma Markers
P-12: Imunno-Oncology Biomarker Assessment by Novel Digital Imaging Algorithms Based on Aqua Technology
P-8: Rapid IVD Fontana-Masson Staining
P-40 Simultaneous detection of RNA and protein using single-molecule RNA in situ hybridization and IHC assays in FFPE tissues
P-3: Automated 5 Min. Mohs Immunohistochemistry
Weird Science Halloween Episode
S/C Learning Snippets - Proximity Ligation Assays – Merging Molecular with Immunohistochemistry (WS28)
S/C Learning Snippets - Proficiency Testing in the Anatomic Pathology Laboratory (WS76)
S/C Learning Snippets - Standardization Across Multiple Sites (WS106)
S/C Learning Snippets - Let's Make Staining H&Easy (WS04)
S/C Learning Snippets - Mohs: Fundamentals and Techniques (WS20)
Scientific Poster Advice: Guy Orchard
Scientific Poster Advice: Claire Johnson
Women in Histology: Inspirational Women
Women in Histology: Work-Life Balance
Women in Histology: Women Business Owners
Women in Histology: Mentor-Mentee Relationships
Women in Histology: Women in Negotiations
Create your
podcast in
minutes
It is Free
DNA Today: A Genetics Podcast
Museum of the Missing
Strange by Nature Podcast
Sasquatch Chronicles
Hidden Brain