Digital Twinning of Interorgan Communications

In this episode of The APS Publications podcast featuring Comprehensive Physiology, we hear from Dr. Lance Fortnow (Illinois Institute of Technology) about his recent Review exploring how artificial intelligence (AI) can play a role in digital twinning of interorgan communication. The human body is an extremely complex system with constant interorgan communication, and AI has been proven effective at modeling complex systems and understanding communication. A digital twin is a complete simulation of a physical process, providing a unique opportunity to simulate real-world physiology and pathophysiological conditions such as aging and various disease states. What role might digital twinning play in researching the effectiveness of therapeutic interventions? Can digital twinning provide a platform for both early career and senior researchers to take a holistic interorgan approach to treating disease? Listen now to find out.

 

Lance Fortnow Digital Twinning of Interorgan Communications Comprehensive Physiology, published February 9, 2025. DOI: doi.org/10.1002/cph4.70002