Episode 6: Evidence with Anne - PPROM Trials

Get ready for the debut episode of "Evidence with Anne" on the thrilling Uterine Sound podcast! Hosted by the dynamic trio, Carla, Mel, and Anne, this episode dives deep into the pulse-pounding world of Preterm Prelabour Rupture of Membranes (PPROM) and its landmark trials.

Hold your breath as they unravel the mysteries of the ORACLE I trial, where antibiotics take centre stage in the epic battle for neonatal outcomes. Discover the power of erythromycin, the hero reducing morbidity and mortality, while the sinister co-amoxiclav raises the spectre of NEC.

But the action doesn't stop there! The ORACLE II trial enters the fray, adding a twist to the tale with its unexpected findings. Brace yourself as the hosts navigate through functional impairments and cerebral palsy, shedding light on the long-term effects of these treatments.

In a heart-pounding showdown, the PPROMT trial takes the spotlight, where immediate delivery faces off against expectant management. Witness the fierce clash of neonatal sepsis rates, respiratory distress, and NICU battles, while APH and caesarean sections add to the adrenaline rush.

And just when you think the excitement is over, the PPROMEXIL trial steps into the ring with its 10-year follow-up! Can it provide the answers to the ultimate question: What are the long-term outcomes for these little warriors?

Listen now on Spotify & Podbean.

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