Dr Gaia Brezzo - Sorting FACS from fiction

Dr Gaia Brezzo narrates her blog written for Dementia Researcher.

Gaia's blog, serves as a comprehensive guide to Fluorescence Activated Cell Sorting (FACS), a cornerstone technique in immunology. With an inviting blend of technical detail and accessible language, the blog demystifies the differences between FACS and flow cytometry, elaborating on their shared principle of using fluorescence to isolate and analyse individual cells. The author offers an insider's view of how FACS is integral to her own research, particularly in studying cell types like microglia and macrophages in the context of strokes. While acknowledging the challenges and limitations inherent to the technique—such as the need for high numbers of viable cells and the loss of spatial information—the blog ultimately underscores the irreplaceable value of FACS in advancing our understanding of disease mechanisms and cellular functions.

Find the original text, and narration here on our website.

https://www.dementiaresearcher.nihr.ac.uk/blog-sorting-facs-from-fiction/

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Dr Gaia Brezzo is a Research Fellow based within the UK Dementia Research Institute at The University of Edinburgh. Gaia's research focuses on understanding how immune alterations triggered by stroke shape chronic maladaptive neuroimmune responses that lead to post-stroke cognitive decline and vascular dementia. Raised in Italy, Gaia came to the UK to complete her undergraduate degree, and thankfully, stuck around. Gaia writes about her work and career challenges, when not biking her way up and down hills in Edinburgh. Follow Gaia on Twitter: @Gaia_Brezzo

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This podcast is brought to you in association with Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support.