Tea's benefits extend to old bones: Japan researchers
Osaka University (Japan), February 24th, 2015
Researchers in Japan say black tea could help treat osteoporosis, a bone condition affecting older people, but admit you need to drink an awful lot of it. Scientists say the humble brew contains an antioxidant that can prevent the loss of bone density commonly seen in old age that makes the elderly more vulnerable to fractures. Researchers found that theaflavin-3 (TF-3), the an...
Tea's benefits extend to old bones: Japan researchers
Osaka University (Japan), February 24th, 2015
Researchers in Japan say black tea could help treat osteoporosis, a bone condition affecting older people, but admit you need to drink an awful lot of it. Scientists say the humble brew contains an antioxidant that can prevent the loss of bone density commonly seen in old age that makes the elderly more vulnerable to fractures. Researchers found that theaflavin-3 (TF-3), the antioxidant, works by inhibiting the function of an enzyme called DNA methyltransferase, which destroys bone tissue. The research, published in the online edition of the US journal Nature Medicine on Monday, found that mice suffering from osteoporosis who were given TF-3 showed recovering levels of bone volume, similar to those of healthymice.
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High vitamin C intake may help elderly maintain immune cells
Tokyo Metropolitan Institute of Gerontology February 20, 2022
Long-term high-dose vitamin C supplementation could help maintain immune functions in ageing, according to research in mice. The Japanese researchers supplemented the diet of vitamin-C deficient mice with either the recommended 20 mg/kg of vitamin C per day or a high dose of 200 mg/kg per day for a year. The results showed a high vitamin C intake could inhibit the age-related decrease in the size of the thymus and maintain thymic output, meaning stable immune cell counts as the mice aged. They said the finding could point to solutions for maintaining immune functions in elderly people. T cells counts were significantly higher in the high dose vitamin C group when compared to the lower dose. They said the change to the thymus may be due to vitamin C's promotion of the production of fibronectin, laminin and collagen.
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Vitamin D2's impact on human health questionable, but vitamin D3 could be important for fighting infections
University of Surrey (UK), February 24, 2022
New research has found significant differences between the two types of vitamin D, with vitamin D2 having a questionable impact on human health. However, the study found that vitamin D3 could balance people's immune systems and help strengthen defenses against viral infections such as COVID-19. In a collaborative study by the Universities of Surrey and Brighton, researchers investigated the impact of vitamin D supplements—D2 and D3—taken daily over a 12-week period on the activity of genesin people's blood. Contrary to widely held views, the research team discovered that both types of vitamin D did not have the same effect. They found evidence that vitamin D3 had a modifying effect on the immune system that could fortify the body against viral and bacterial diseases.
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What’s in Mushrooms That Supports Healthy Aging
Life Extension, February 23, 2022
A landmark study published in April 2021 followed the dietary patterns of 15,000 Americans for nearly 20 years. Those who consumed mushrooms in their diet had a 16% lower overall mortality risk. When one serving a day of mushrooms was ingested in place of processed or red meats, there was a 35% reduction in all-cause mortality. A trend toward even lower mortality was found in people who consumed higher amounts of mushrooms. So, what's in mushrooms that enables people to live longer? It turns out that mushrooms contain more of an amino acid called L-ergothioneine than other food sources. L-ergothioneine appears to protect DNA and reduce the shortening of telomeres. L-ergothioneine is an amino acid not produced by the human body. L-ergothioneine levels peak in early adulthood and steadily decline with age as the body loses its ability to accumulate this powerful nutrient. It is found in the highest concentration in mushrooms and other fungi. When L-ergothioneine intake in America was compared with intake in Europe, researchers found that Europeans had greater longevity possibly due to higher L-ergothioneine intake. Most tissues of the body contain L-ergothioneine. It is concentrated in higher degrees in cells at greatest risk of injury due to oxidative stress and inflammation, including blood, bone marrow, eye lens, brain, liver, and skin. L-ergothioneine transporters are also found in the placenta and mammary glands, suggesting its importance in the early development of the embryo and newborn children.
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