Inflection Point

Inflection Point

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Inflection Point traces emerging ideas in science to their surprising roots. With help from C&EN's vast, 100-year archive, we find the origins of modern breakthroughs, and tease out three different pieces of the puzzle that lead to our current moment.

Episode List

Bonus: Celebrating 1 year of Inflection Point!

Mar 23rd, 2026 1:38 PM

Exactly one year ago, co-hosts David and Gina embarked on their time-traveling journey thorugh science history. Along the way they've traced the unlikely origins of microplastics, relived the nauseating experiment behind the first battery, and fished for the surprising creatures that helped scientists develop GLP-1 drugs. Join them as they surprise each other with their favorite moments from the show's first year. C&EN's award-winning podcast Inflection Point leans on our 100-year archive to trace headline topics in science today back to their disparate and surprising roots. In each episode, we explore three lesser-known moments in science history that ultimately led us to current-day breakthroughs. With help from expert C&EN reporters, this show examines how discoveries from our past have shaped our present and will change our future. Subscribe to Inflection Point now on Apple Podcasts, Spotify, or wherever you get your podcasts.

The electric innovations that brought lithium-ion batteries online

Dec 17th, 2025 1:15 PM

C&EN's award-winning podcast Inflection Point leans on our 100-year archive to trace headline topics in science today back to their disparate and surprising roots. In each episode, we explore three lesser-known moments in science history that ultimately led us to current-day breakthroughs. With help from expert C&EN reporters, this show examines how discoveries from our past have shaped our present and will change our future. In the last episode of our second season, hosts David Anderson and Gina Vitale charge up the time machine to relive three historical moments that led to the lithium-ion battery. They also bring in C&EN reporter Prachi Patel to discuss the shortcomings of lithium-ion batteries, whether we're facing a lithium shortage, and new battery chemistry still on the horizon. Subscribe to Inflection Point now on Apple Podcasts, Spotify, or wherever you get your podcasts.

The ancient, 'juicy' origins of antibiotic resistance

Dec 3rd, 2025 1:25 PM

C&EN's award-winning podcast Inflection Point leans on our 100-year archive to trace headline topics in science today back to their disparate and surprising roots. In each episode, we explore three lesser-known moments in science history that ultimately led us to current-day breakthroughs. With help from expert C&EN reporters, this show examines how discoveries from our past have shaped our present and will change our future. In the third episode of our second season, hosts David Anderson and Gina Vitale travel back in time to relive three historical moments that ultimately led to our current understanding of antibiotic resistance. They also bring in C&EN reporter Rowan Walrath to offer a glimpse into a doomsday-scenario future when antibiotics are no longer effective. Subscribe to Inflection Point now on Apple Podcasts, Spotify, or wherever you get your podcasts.

The era-spanning epiphanies that enabled gene editing

Nov 19th, 2025 2:30 PM

Hosts David and Gina explore how scientists over the centuries unlocked the ability to edit our genes C&EN's award-winning podcast Inflection Point leans on our 100-year archive to trace headline topics in science today back to their disparate and surprising roots. In each episode, we explore three lesser-known moments in science history that ultimately led us to current-day breakthroughs. With help from expert C&EN reporters, this show examines how discoveries from our past have shaped our present and will change our future. In the second episode of our second season, hosts David Anderson and Gina Vitale travel back in time to relive three historical moments that ultimately led to scientists being able to edit genes. They also bring in C&EN reporter Max Barnhart to offer a glimpse into the future of gene editing technology. Subscribe to Inflection Point now on Apple Podcasts, Spotify, or wherever you get your podcasts.

How under-appreciated critters inspired GLP-1 drugs

Nov 5th, 2025 2:30 PM

In the first episode of our second season, hosts David Anderson and Gina Vitale travel back in time to relive three historical moments that led to blockbuster drugs like Ozempic and Wegovy. They also talk with C&EN reporter Aayushi Pratap about how future GLP-1 drugs may expand on the current slate of options. C&EN's latest podcast, Inflection Point, leans on our 100-year archive to trace headline topics in science today back to their disparate and surprising roots. In each episode, we explore three lesser-known moments in science history that ultimately led us to current-day breakthroughs. With help from expert C&EN reporters, this new show examines how discoveries from our past have shaped our present and will change our future. Subscribe to Inflection Point now on Apple Podcasts, Spotify, or wherever you get your podcasts.

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