Equity

The musician-turned-biotech-founder waiting to fundraise

When Grammy-nominated singer-songwriter Aloe Blacc got COVID despite being vaccinated and boosted, he tried to fund research for a better solution. What he quickly found out? You can't just write a check in biotech. Regulators require a commercialization plan, and philanthropy doesn't move science through clinical trials or get you a license on university IP. Now, he's bootstrapping a cancer drug platform targeting pancreatic cancer, a disease that kills 90% of its patients, and intentionally waiting to raise from his network until peer-reviewed papers can make his case.  On this episode of TechCrunch's Equity podcast, Rebecca Bellan sits down with Aloe Blacc to talk about what happens when a creator decides to build instead of just invest, how Aloe is watching AI reshape both the biotech and music industries in real time, and his thoughts on who actually wins.  Listen to the full episode to hear:  How he’s navigating a world where credibility is earned in data, not fame  How a University of Houston molecule discovery platform could cut years off drug development timelines  Why he thinks record labels, not artists or AI companies, will ultimately control the economics of AI-generated music  What Suno taught him about prototyping, and why his next album will still be recorded with live musicians  Subscribe to Equity on YouTube, Apple Podcasts, Overcast, Spotify and all the casts. You also can follow Equity on X and Threads, at @EquityPod.  Learn more about your ad choices. Visit megaphone.fm/adchoices

Luma AI's Amit Jain on why most world model companies are getting it completely wrong

LLMs may have kicked off this AI boom, but the ceiling is closer than the hype suggests. As models run out of text data to train on, the companies and investors paying attention are already moving on. The next wave isn't better chatbots; it's machines that can understand the physical world. Luma AI, the Bay Area lab that raised over $1.4 billion from a16z, Nvidia, and Amazon, is betting on exactly that.  On episode of TechCrunch's Equity podcast, we’re bringing you a conversation Rebecca Bellan sat down with Amit Jain, co-founder and CEO of Luma AI, at Web Summit Qatar. Together, the pair dug into where the next trillion-dollar AI opportunity actually gets built, and whether the companies chasing it even know what they're building yet.  Listen to the full episode to hear about:  Why video, audio, and images are the real frontier for AI training data, not text  What an "intelligent world model" actually is, and why Jain thinks most companies building them are getting it completely wrong  The case for why AI won't kill creative jobs, and why Jain thinks studio heads are the real problem  How the path from video generation to robotics to AGI is simpler than anyone's making it sound  Subscribe to Equity on YouTube, Apple Podcasts, Overcast, Spotify and all the casts. You also can follow Equity on X and Threads, at @EquityPod.  Chapters:  00:00 Intro  01:13 Why LLMs are hitting a ceiling  02:43 The data problem & what comes after LLMs  04:30 What actually makes a world model a world model  06:05 Why 3D data is a dead end  07:39 What Luma is building next  09:08 How much humans stay in the loop  10:00 Near-term use cases for agentic video  11:22 Will AI kill jobs in film & production?  13:30 Why the entertainment industry is already dying  15:27 Why we actually need more content, not less  17:46 Luma's roadmap: generation, understanding, and robotics  19:54 Outro  Learn more about your ad choices. Visit megaphone.fm/adchoices

Snowflake’s transition from storing data to shipping with it

Snowflake is betting that the future of AI isn’t just analyzing data, it’s acting on it. That means a shift away from chatbots and toward autonomous agents that can actually get work done. And Snowflake is reorganizing fast to keep up, from shipping hundreds of AI features to restructuring teams along the way.On this episode of TechCrunch’s Equity podcast, Rebecca Bellan sits down with Snowflake CEO Sridhar Ramaswamy to unpack the company’s transformation and what it signals about where AI is headed next. Listen to the full episode to hear: Why Ramaswamy believes the chatbot era is ending and the agentic era is beginning. How Snowflake is evolving from a data warehouse into an AI and applications platform. What “shipping with your data” actually looks like in practice. Why the company is making big internal changes to support its AI push. Subscribe to Equity on ⁠YouTube⁠,⁠ Apple Podcasts⁠,⁠ Overcast⁠,⁠ Spotify⁠ and all the casts. You also can follow Equity on⁠ X⁠ and⁠ Threads⁠, at @EquityPod.  Chapters: 00:00 Intro 00:17 Snowflake’s AI shift and agentic future 01:45 Why 2026 marks the end of chatbots 04:09 Cortex Code, Snowflake Intelligence, and new products 06:09 Who benefits: non-technical users & enterprises 07:35 Adoption challenges and why AI pilots fail 12:11 How AI is reshaping jobs and skills 14:39 Layoffs, automation, and the future of documentation 18:37 Snowflake’s evolution into an AI platform 21:04 Competition: Databricks, hyperscalers, and AI giants 25:01 Outro Learn more about your ad choices. Visit megaphone.fm/adchoices

Space: the final frontier of AI infrastructure

Tech companies are racing to build data centers in space, pitching orbital compute as the next frontier for AI infrastructure, even as the technical and economic realities remain far from clear. Add in OpenAI’s massive $122 billion round and Bluesky’s latest AI backlash, and the message is clear: The future of AI is being shaped as much by ambition and hype as it is by real-world constraints.  On this episode of TechCrunch’s Equity podcast, Kirsten Korosec, Anthony Ha, and Sean O’Kane unpack these massive capital bets, user backlash, and off-world compute plans along with Whoop’s major valuation and the literal downfall of robot Olaf.   Listen to the full episode to hear about:  OpenAI’s $122 billion fundraise and what its near-trillion-dollar valuation says about expectations for AI.   Whoop’s $575 million raise and the shift toward “wearables 2.0” (and what happens to all that data).   Bluesky’s AI-powered feed builder and why it triggered a major user backlash.   The rise of data centers in space and whether they are financially or physically feasible.   Subscribe to Equity on YouTube, Apple Podcasts, Overcast, Spotify, and all the casts. You also can follow Equity on X and Threads, at @EquityPod.  Chapters: 00:00 Intro 00:20 A humanoid Olaf robot collapses at Disneyland Paris 03:30 OpenAI raises $122B at an $852B valuation 11:30 Whoop lands $575M and bets big on wearable data  18:50 The risks (and value) of personal health data 23:00 Bluesky’s AI feed builder sparks backlash 30:00 Can Bluesky keep growing — and compete with X? 36:30 The race to build data centers in space 44:30 SpaceX, Starlink, and the business of orbital compute 49:30 Outro  Learn more about your ad choices. Visit megaphone.fm/adchoices

Why private wealth is cutting out the VC middleman

The VC middleman is getting cut out faster than anyone expected. Family offices and private wealth firms are going direct: writing checks, taking board seats, even incubating companies from scratch. And more founders are starting to notice. In February alone, family offices made 41 direct investments, including one Midwest-based firm that led a $230 million Series B into an AI chip startup.    On this episode of TechCrunch's Equity podcast, Rebecca Bellan caught up with Mitch Stein and Ari Schottenstein, founder and head of alternatives at ARENA Private Wealth, to find out what this shift means for founders, cap tables, and the future of AI investment.    Listen to the full episode to hear:  How Arena landed the lead on Positron's $230 million Series B, and why the CEO specifically wanted them on his cap table  How Arena does due diligence on technical companies  What "tourist capital" actually looks like, and the red flags founders should watch for as family offices flood into AI deals  Why some VCs are quietly unhappy about this trend (and why Arena thinks that's their problem)  Subscribe to Equity on YouTube, Apple Podcasts, Overcast, Spotify and all the casts. You also can follow Equity on X and Threads, at @EquityPod.    Chapters:  00:00 Intro   03:13 Why family offices are going direct now  06:03 The gen 2 & gen 3 family office shift  07:22 Is this strategic or just AI FOMO?  10:17 How Arena got into the Positron deal  14:30 Why founders want private wealth on their cap table  18:31 Due diligence on technical companies  21:56 Red flags founders should watch for  25:04 Are VCs threatened by this trend?  27:47 Taking board seats & level of involvement  34:17 Outro  Learn more about your ad choices. Visit megaphone.fm/adchoices