The Kris Gethin Podcast

238. Why Everybody Is Suddenly Using Empagliflozin

Jardiance has exploded in the longevity and fat loss world, but most people still have no idea how it actually works. You hear about glucose dumping, ketone shifts, inflammation changes and kidney filtration, but the mechanism is rarely explained in a way that makes sense. In this episode I break it down with zero nonsense. You will learn how empagliflozin, the compound in Jardiance, blocks SGLT2 in the kidneys, forces glucose into the urine and creates a consistent calorie leak each day. I show you how that impacts fat loss, metabolic flexibility, ketone production, hydration and long term cardiometabolic health. I also compare Jardiance to retatrutide, GLP-1s, tesamorelin, metformin and tesofensine so you understand which tools target appetite, which target the liver, which target the kidneys and which have the biggest impact on body composition and longevity. If you want a clear breakdown of where Jardiance actually fits in a real protocol, this episode gives it to you straight. What's Discussed: (00:02) Why Jardiance Is Suddenly a Longevity Tool (05:48) How Jardiance Forces Glucose Out Through the Kidneys (08:26) The Truth About Fat Loss Results on Jardiance (12:00) GLP-1s vs Retatrutide vs Jardiance (17:16) Jardiance vs Metformin for Metabolic Health (21:05) Tessofensine, Peptides and Where Jardiance Fits Find more from Kris: Website: https://www.krisgethin.com/   Instagram: @krisgethin  Youtube: https://www.youtube.com/krisgethin 2 Shred: https://www.unmatchedsupps.com/products/2shred    Thank you to our sponsors:  Timeline Nutrition — 20% off for my listeners → timeline.com/GETHIN LVLUP →  If you want to support your gut, tighten up your recovery, and keep your metabolism firing clean, grab TOTAL RECOMP from LVLUP Health. Use code GETHIN for 20% off at lvluphealth.com    Products & Compounds Mentioned in This Episode Prescription Medications Jardiance (empagliflozin / SGLT2 inhibitor) Metformin Peptides & Related Compounds Tesamorelin Ipamorelin CJC (often paired with ipamorelin) Tesofensin Reditudite / Retatutide GLP-1 Agonists Mentioned Semaglutide / Ozempic Other Tools / Supplements Referenced GDA (general glucose disposal agents) ElectroShred (electrolytes): https://www.unmatchedsupps.com (Code: KGC10) Carbohydrates from Vitargo  

237. 6 Tips to Help Prevent Alcohol Damage Over the Holidays

Most people underestimate how much alcohol destroys their progress during the holidays. They think a few drinks only affect their sleep or recovery, but the real damage happens on a deeper level. Inflammation shoots up, blood sugar swings all over the place, the liver gets overloaded, electrolytes crash, mitochondria slow down, and the gut takes a beating. That is why one night out can leave you feeling sluggish, puffy, and unmotivated for days. In this episode you get a clear protocol to reduce that damage fast. You will learn how to support your liver with glutathione, control oxidative stress with hydrogen tablets, restore minerals with electrolytes, use bitters for digestion, protect your mitochondria with ESS60, and stabilize blood sugar with GDA. I give you the exact timing for each tool so you can bounce back cleanly and stay on track. This is your complete plan to drink smarter, recover faster, and keep your progress intact through the holidays. What's Discussed: (00:01) What Alcohol Is Really Doing Inside Your Body (03:00) Why Hangovers Hit Harder Than They Should (05:21) The Glutathione Timing That Makes a Difference (08:11) Hydrogen and Electrolytes for Next Day Recovery (14:53) The Complete Holiday Damage Control Protocol Find more from Kris: Website: https://www.krisgethin.com/   Instagram: @krisgethin  Youtube: https://www.youtube.com/krisgethin 2 Shred: https://www.unmatchedsupps.com/products/2shred    Thank you to our sponsors:  Timeline Nutrition — 20% off for my listeners → timeline.com/GETHIN LVLUP →  If you want to support your gut, tighten up your recovery, and keep your metabolism firing clean, grab TOTAL RECOMP from LVLUP Health. Use code GETHIN for 20% off at lvluphealth.com  Products Mentioned in This Episode  Glutathione Support • Cell Shield by Biostack Labs — https://biostacklabs.com/ • Setria Liposomal Glutathione Hydrogen Tablets • Drink HRW — https://drinkhrw.com/pages/h2-in-sports (Code: GETHIN for 10% off) Electrolytes • Electra Shred by Unmatched — https://www.unmatchedsupps.com (Code: KGC10) Bitters • Dr. Shade's Bitters No. 9  Mitochondrial Support • MyVitalC (ESS60) — https://www.myvitalc.com/gethin/ (Code: GETHIN for 15% off) Blood Sugar Support • GDAID by Biostack Labs — https://biostacklabs.com/ Protein + Amino Acids • Grass-fed protein shake • Longevity EAAs by Unmatched — https://www.unmatchedsupps.com (Code: KGC10)

236. 10 Things to Do to Prevent Weight Gain During the Holidays

Most people don't realize how much of their holiday weight gain has nothing to do with "bad food choices" and everything to do with unplanned habits, skipped movement, and metabolic chaos. They write December off as a free-for-all, promise themselves they'll start fresh in January… and then spend the next two months undoing damage that was completely avoidable. In this episode, I'm giving you the plan that stops that cycle cold. I'm walking you through the 10 strategies I personally use to stay lean, strong, and in control through the holidays; without skipping the celebrations.  From feast-day training and nutrient partitioning to strategic fasting and metabolism-supportive supplementation, you'll learn exactly how to handle travel, parties, big meals, alcohol, stress, and disrupted routines without sacrificing results.  This episode is your full playbook for navigating the holidays like a pro: how to train, how to eat, what supplements actually matter, which habits blunt fat gain the fastest, and how to walk into January ahead of everyone else. If you've ever felt like the season derails your progress, this will show you what's truly possible. What's Discussed: (00:00) Preventing Weight Gain During the Holidays (02:33) Feast-Day Training & Nutrient Partitioning (05:32) Strategic Fasting for Metabolic Control (08:20) Holiday Health, Supplements & Blood Sugar Strategies (17:33) Holiday Fitness, Discipline & Nutrition Mastery   Find more from Kris: Website: https://www.krisgethin.com/   Instagram: @krisgethin  Youtube: https://www.youtube.com/krisgethin 2 Shred: https://www.unmatchedsupps.com/products/2shred    Thank you to our sponsors:  Timeline Nutrition — 20% off for my listeners → timeline.com/GETHIN LVLUP →  If you want to support your gut, tighten up your recovery, and keep your metabolism firing clean, grab TOTAL RECOMP from LVLUP Health. Use code GETHIN for 20% off at lvluphealth.com   

235. Anti Aging Medications for Longevity (The Truth No One Shares)

Most people have no idea what's really happening in the longevity world. They hear "anti-aging" and think of fasting windows and cold plunges. Meanwhile, some of the most powerful tools are prescription-only compounds that almost never get discussed publicly. I've been experimenting with several of them for years, tracking how they impact my performance, recovery, bloodwork, and training cycles… and in this episode, I'm breaking that silence. I'm walking you through the three medications I personally use, why I use them, the biology they target, and how they fit into my longevity and performance blocks. But I'm also giving you the natural alternatives that hit similar pathways without stepping into prescription territory. I'm covering everything from metabolic control to detoxification to skin regeneration, and how to think about timing, cycling, and longevity from an athlete's perspective. This episode will open your eyes to what's really possible. What's Discussed: (00:05) The anti-aging medications I personally use and why I cycle them (02:41) How I approach mTOR modulation inside my training blocks (09:07) The metabolic compound I only take under certain conditions (15:46) The prescription binder I use after travel or high exposure (18:52) When I switch to natural binders instead of pharmaceuticals (21:23) The skin-regeneration protocol I rotate between weeks Thank you to our sponsors: NAD + Cell Shield from Biostack Labs → https://biostacklabs.com/krisBiOptimizers — code KRIS10 for 10% off → https://bioptimizers.com/Timeline Nutrition — 20% off for my listeners → timeline.com/GETHIN LVLUP →  If you want to support your gut, tighten up your recovery, and keep your metabolism firing clean, grab TOTAL RECOMP from LVLUP Health. Use code GETHIN for 20% off at lvluphealth.com    Find more from Kris: Website: https://www.krisgethin.com/  Instagram: https://www.instagram.com/krisgethin/  Youtube: https://www.youtube.com/krisgethin   

234. 12 Things The Supplement Industry Doesn't Want You to Know

Most people assume supplements are helping their health and performance. The reality is that a large part of the industry is built on cheap ingredients, artificial additives, and labels designed to look impressive instead of delivering results. I've been in this industry for nearly three decades as a writer, editor, and brand owner, and I've seen exactly what happens behind the labels.  In this episode, I break down twelve things supplement companies hope you never learn, including how many amino acids are sourced from bird feathers and human hair, why artificial sweeteners disrupt your gut and hormones, how high-stim pre-workouts create dependency instead of energy, and why grain-fed whey can carry glyphosate residues.  We also cover diluted store-brand formulas, contaminated botanicals, heavy metals in vegan proteins, and influencer marketing tactics that hide the truth. After this episode, you'll know how to read your labels, choose better products, and protect your health. This episode is your supplement audit. After you listen, go check your cupboard. Some of what you find may surprise you. What's Discussed: (00:02) The Supplement Industry's Dirty Secrets (01:08) What's Really in Your Amino Acids (03:24) Generic vs. Clinically Tested Ingredients (05:56) Artificial Sweeteners and Your Gut (10:24) The Cost of High-Stim Pre-Workouts (12:31) Why Retail Shelf Products Are Watered Down (14:45) Contaminated Botanicals and Heavy Metals Thank you to our sponsors:  NAD + Cell Shield from Biostack Labs → https://biostacklabs.com/krisBiOptimizers — code KRIS10 for 10% off → https://bioptimizers.com/Timeline Nutrition — 20% off for my listeners → timeline.com/GETHIN LVLUP → If you want to support your gut and recovery, use code GETHIN for 20% off GI Repair at lvluphealth.com    Find more from Kris: Website: https://www.krisgethin.com/    Instagram: @krisgethin  Youtube: https://www.youtube.com/krisgethin