Unbreakable Spirit: Living with Lynch Syndrome, Cancer, and Finding Purpose with JJ Singleton

Lynch Syndrome Series

In recognition of Lynch Syndrome Awareness Day on March 22 each year, The Positive Gene Podcast is featuring a five-part series exploring what it means to live with Lynch syndrome; from diagnosis and treatment to advocacy, prevention, and long-term survivorship.

Note: This episode includes brief discussion of depression and suicidal thoughts. Please listen with care. Support resources are included below.

 

Episode Overview

In this episode, Sara Kavanaugh speaks with JJ Singleton, a young adult colorectal cancer survivor and advocate living with Lynch syndrome.

Diagnosed at just 27, JJ shares the experience of noticing symptoms but not initially acting on them, the reality of navigating cancer treatment in a rural setting, and what it meant to later learn his diagnosis was connected to a hereditary cancer condition.

This conversation goes beyond diagnosis. JJ speaks openly about the mental health challenges that came with long-term treatment, including periods of deep depression, and how therapy, connection, and advocacy helped him find a path forward.

Today, JJ uses his experience to support others through advocacy, peer connection, and patient advisory work, helping ensure that the realities of young adult cancer are better understood.

This episode offers both perspective and practical insight for patients, families, and those supporting individuals navigating hereditary cancer risk.

Key Takeaways

• Do not ignore symptoms. Even at a young age, changes in your body are worth investigating.
• Advocate for yourself. If something doesn’t feel right, seek a second opinion.
• Genetic testing provides clarity. Understanding hereditary risk can guide screening and treatment decisions.
• Mental health is part of the journey. Support, including therapy, can play a critical role.
• Community matters. Connection with others facing similar challenges can reduce isolation.
• There are more options today than many people realize. Treatment and research continue to evolve.

Resources Mentioned in this episode:

Mental Health Support

• 988 Suicide & Crisis Lifeline (U.S.)
  Call or text 988 for 24/7, free, confidential support

Lynch Syndrome & Hereditary Cancer

• AliveandKick’n
  Patient-led Lynch syndrome advocacy and education
• Fight Colorectal Cancer (Fight CRC)
  Research, advocacy, and patient support
• Colon Cancer Coalition
  Screening awareness and education
• Other Lynch Syndrome Resources:
  • Lynch Syndrome Awareness and Education
  • Jacqueline Rush Foundation

Young Adult & Peer Support

• Stupid Cancer
  Support and programming for young adults with cancer
• Man Up to Cancer
  Peer support community focused on connection and reducing isolation

Why This Episode Matters

JJ’s experience highlights that hereditary cancer is not limited by age, geography, or expectation.

His voice brings attention to:

• the reality of young adult cancer
• the importance of early awareness
• the need for accessible care and support
• and the role of advocacy in improving outcomes for others

Listen & Share

If this episode resonates, consider sharing it with someone who may benefit—from patients and families to healthcare providers and advocates.

🎧 The Positive Gene Podcast

 

Connect with JJ

• Follow JJ Singleton on social media to follow his advocacy work @jj5145 on Instagram

Connect with The Positive Gene Podcast

• www.positivegenepodcast.com
• Instagram: @positivegenepodcast