On AIRR - Immune receptors in the clinic
Science:Life Sciences
Dr. Adi Barzel is an associate professor in the department of Biochemistry & Molecular Biology at Tel Aviv University, Tel Aviv, Israel. Adi is President at Israeli Society of Gene and Cell Therapy.
Following Adi’s long standing interest in gene editing, we discuss the therapeutic potential based on Adi’s recent paper “In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice” (Nat Biotechnol.; 2022; https://doi.org/10.1038/s41587-022-01328-9). We also briefly touch on a second paper on some of the problems with CRISPR-Cas9 gene editing (“Frequent aneuploidy in primary human T cells after CRISPR-Cas9 cleavage”; Nat Biotechnol.; 2022; https://doi.org/10.1038/s41587-022-01377-0)
iReceptor Plus Seminar Series - Nur-Taz Rahman from 10x Genomics and Kazuyoshi Ishigaki, Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Japan will present on October 27th (https://www.ireceptor-plus.com/news-and-events/seminars/)
The episode is hosted by Dr. Ulrik Stervbo and Dr. Zhaoqing Ding.Comments are welcome to the inbox of onairr@airr-community.org or on social media under the hashtag #onAIRR. Further information can be found here: https://www.antibodysociety.org/the-airr-community/airr-c-podcast
On AIRR 15: Germline databases or adventures into the allelic underworld with Dr. Corey Watson and Dr. William Lees
On AIRR 14: Data protection and data sharing with Alexander Bernier
On AIRR 13: Disease diagnostics using machine learning with Maxim Zaslavsky and Dr. Scott D. Boyd
On AIRR 12: T-cell receptor-mimetic antibodies and immunoinformatics with Prof. Dr. Charlotte Deane
On AIRR 11: Software as a Medical Device (SaMD) with Dr. Xenophon Papademetris
On AIRR 10: Characterising B Cell Lymphomas or Profiting from a Focus on B Cells in Health and in Disease with Dr. Ralf Küppers
On AIRR 9: The ImmunoMind or wielding an AI for repertoire insights with Vadim Nazarov
On AIRR 7: Quality Controls in AIRR-Seq Assays or Handling the Catastrophe with Dr. Encarnita Mariotti-Ferrandiz
On AIRR 6: Data Sharing or Finding Glory, Fame and a Big Pile of Gold with Dr. Brian Corrie and Dr. Scott Christley
On AIRR 5: Machine learning and AIRR or Looking for the needle in a needle stack with Dr. Lindsay Cowell and Dr. Victor Greiff
On AIRR 4: Understanding and engineering immune repertoires with Dr. Jacob Glanville
On AIRR 3: Outlining chronic lymphocytic leukemia with Dr. Anton Langerak
On AIRR 2: Establishing an AIRR-Seq framework with Dr. Lindsay Cowell
On AIRR 1: MRD with Dr. Luning Prak
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