The Hunter Williams Podcast

The MOTS-c Masterclass | Complete Researcher’s Guide (2026)

Links, cheatsheet, private group and more: ⁠https://hunterwilliamshealth.com/linksIn this masterclass I break down what MOTS-c actually is. It's a tiny peptide your mitochondria make when you exercise. It's the only major peptide coded inside the mitochondrial genome, not the cell nucleus.I get into how it flips the AMPK switch, your cell's main fuel gauge. I cover the dual action that lets it travel into the nucleus and turn on antioxidant genes. That part makes it pretty unique.Then I walk through the practical stuff. Who's a good candidate and who should skip it. My full dosing tiers, from a 250mcg screening dose up to 5mg. Cycling, reconstitution, and how I pair it with SS-31 and humanin.I also cover the side effect nobody warns you about. Around 10% of people react badly, and some of those reactions are serious. That's why I start low and work up slowly.A heads up on the evidence. Most of the exciting data is still animal models. Human data is thin, so I flag where I'm extrapolating.MOTS-c is more bioactive than its reputation suggests. Treat it with respect and it rewards you.

The BPC-157 Masterclass | Complete Users Guide (2026)

Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksBPC-157 is the peptide almost everyone starts with. In this masterclass I walk through why, and where the hype gets ahead of the evidence.We have about 30 years of animal studies on this one. We have fewer than 30 human subjects in published research. I keep that line clear the whole way through.I cover what BPC actually does. It helps the body repair tissue. It works on the gut, tendons, ligaments, and even the brain in animal models. It is not a steroid and it does not build muscle on its own. I explain how it works, who it helps, and who should skip it.Then we get practical. Dosing tiers, how to reconstitute the vial, how to inject near an injury, and how long before you feel anything.I tackle the cancer question head on. The fear is plausible on paper. The data does not really back it up. I tell you exactly where I land.We also cover cycling, the Wolverine stack with TB-500, oral versus injectable, and the FDA shift happening right now.Even if you already know this one, you will probably pick up something. If you are new to peptides, start here.

Saturday Morning Coffee Talk 6/20/26

Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/links

The KPV Masterclass | The Complete User's Guide

Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksKPV is the most underrated peptide out there. Almost nobody talks about it. In my opinion it should be one of the most demanded peptides we have. If I had to choose, I'd take it over BPC and TB-500 every single time.Here's why. KPV is a tiny three amino acid fragment of alpha-MSH. It directly blocks NF-kappa B, the master switch your body uses to turn inflammation on. Most peptides work around the edges. KPV shuts the alarm off at the door.In this one I cover all of it. What KPV is and how it works. Who actually benefits. Dosing by tier and by purpose. How to stack it with BPC, TB-500, LL-37, and your GLP-1. What to track on bloodwork. Cycling, sequencing, troubleshooting, and a full FAQ.If you've ever run a protocol that worked and then stalled out, this one is for you. Inflammation is almost always the rate-limiting step in healing.Make sure you're on the email list. And come join us in the Axion Collective for live coaching every Thursday.⚠️ For research and entertainment purposes only. ⚠️

The Tesamorelin Masterclass | The Complete User's Guide (2026)

Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksTesamorelin is one of the few peptides I've seen actually move the needle on body composition. So I made a full masterclass on it.This is the user's guide as it stands in 2026. I cover what tesamorelin is, how it works, and the best practices I'd recommend for using it.We get into the growth hormone axis and why a GHRH is different from a GHRP. I break down the clinical data, the 15% visceral fat reduction, the liver fat numbers, and the cognition research almost nobody talks about.Then we get practical. Dosing, timing, fasted injections, and the cycling patterns I actually use. I share why I stay at one milligram instead of two and what the water retention tradeoff looks like at higher doses.I also cover stacking with testosterone and GLP-1s, reconstitution, injection technique, side effects, and the people who should skip this one entirely.I'm honest about the limits too. Some of this evidence is strong and some of it isn't. I tell you which is which.If you're thinking about tesamorelin or already using it, this is everything I'd want you to know.