The Dr. Gabrielle Lyon Show

The Truth About Microplastics No One Is Telling You

You might think microplastics are just an environmental nuisance that passes through your body, but the latest tissue studies tell a very different story. As a physician, Dr. Gabrielle Lyon breaks down where the science lands, past both the fear-mongering and the dismissiveness.In this solo episode, Dr. Gabrielle Lyon discusses:Why over 58% of patients in a landmark NEJM study had plastic embedded in their arterial plaque and the 4.5x higher risk of heart attack, stroke, and death that came with itHow microplastics act as a "Trojan horse," carrying endocrine-disrupting chemicals into your blood, testes, brain, and reproductive tissueWhy perimenopause and menopause are an especially vulnerable window for plastic-driven hormone disruptionThe five low-cost "Lyon Protocol" rules to cut your exposure, starting with never microwaving plastic and letting food cool before you store itThis matters because you don't need to overhaul your life or wait twenty years for perfect data to protect your cellular health; you just need the handful of small, automated decisions that move the needle on your metabolic and hormonal baseline.Thank you to our sponsors:Our Place - Upgrade your kitchen with Our Place today. Visit https://bit.ly/3RnCYH0 and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Timeline - Get 20% off your Mitopure order at https://bit.ly/4wJpFzZ Bon Charge - Save 15% at https://bit.ly/44bIoYx with code DRLYON Explore More from Dr. Gabrielle LyonWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyon Chapters00:00 - Introduction01:30 - What microplastics and nanoplastics are03:00 - Where plastics show up inside us04:30 - The UCSF systematic review06:10 - Inflammation, cytokines, and thyroid07:40 - Plastic in arterial plaque and the 4.5x risk10:10 - The strongest skeptic arguments13:00 - Lead, asbestos, and trans fats14:40 - The Trojan horse for hormone disruptors16:10 - Reproductive aging and menopause17:50 - Where Dr. Lyon lands19:40 - The Lyon protocol: five rulesIf you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Cardio vs Strength Is a Myth and the Science Proves It - Alyssa Olenick

You've been told that 10,000 steps a day is enough to keep you healthy but when it comes to your bones and your muscles, walking falls short, and the science explains exactly why. The real drivers of strength, bone density, and lasting health are load, intensity, and resistance, not just movement.In this episode, Dr. Gabrielle Lyon sits down with Dr. Alyssa Olenick, a PhD in exercise metabolism and ultramarathoner who blends endurance and strength training, to discuss:Why the "interference effect," the fear that cardio cancels your strength gains, is overblown for almost everyone, and what causes the carryover fatigueHow most women train too lightly, believing they're at a 9 out of 10 when they're closer to a 5, and never trigger real muscle adaptationWhy estrogen is not the primary driver of muscle, resistance training is, and what that means through the menopause transitionThe early warning signs of low energy availability, including cycle changes that show up long before a missed period, and the rapid bone loss that followsHow to structure strength, power, and cardio together, and fuel it properly without sabotaging recoveryYou'll walk away knowing how to train for strength, power, and bone density that lasts and why being undertrained, not fragile, is the real problem for most women.The July Forever Strong Foundations Challenge begins July 6, 2026. This 4-week challenge is designed to help you build a stronger, more energized you through sustainable nutrition, training, and lifestyle habits. Register here: https://bit.ly/4p3DW7UThank you to our sponsors:Our Place - Upgrade your kitchen with Our Place today. Visit https://bit.ly/3RnCYH0 and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.Timeline - Get 20% off your Mitopure order at https://bit.ly/4wJpFzZBon Charge - Save 15% at https://bit.ly/44bIoYx with code DRLYONExplore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Alyssa Olenick at:Website: https://doclyssfitness.com/Instagram: https://www.instagram.com/doclyssfitness/The Running Ebook: https://doclyssfitness.com/running/Connect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction02:09 - Hybrid vs. concurrent training defined05:03 - Where beginners should start10:12 - Movement vs. exercise vs. training11:30 - The interference effect: the boogeyman16:55 - Nervous system fatigue and bar speed20:07 - Why running fatigues you more than cycling26:04 - Fuel use, fat oxidation, and the crossover34:39 - Mitochondria and metabolic flexibility39:13 - What we don't know about women's physiology44:18 - Type one vs. type two muscle fibers46:00 - Testosterone, training age, and muscle gain48:02 - What we confidently know about women and muscle49:43 - Estrogen is not the muscle driver53:14 - Menstrual cycle, performance, and perception58:03 - Training the mind, not just the body1:02:18 - The aerobic guidelines and doing more1:06:26 - The 2026 resistance training guidelines1:16:49 - Squat, hinge, push, pull explained1:22:04 - Why walking isn't enough for bone1:26:14 - Power, plyometrics, and power-penia1:35:33 - Programming cardio without killing gains1:41:03 - Low energy availability and warning signs1:47:38 - Protein and carbs for the hybrid athlete1:53:52 - The seasons approach: spend a year liftingIf you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

The Testosterone Myth Men Have Been Lied To About

You were told your testosterone is "normal" so why do you still feel exhausted, weak, and off? The number on your lab report was never built for you, and your own genetics may be the reason it doesn't match how you feel.In this solo episode, Dr. Gabrielle Lyon discusses:Why the standard 300–1000 ng/dL range ignores your age, comorbidities, and genetics, and why two men with identical labs can feel completely differentHow CAG repeats determine whether your body "catches" the testosterone you produce, meaning you might need 400 to feel great while someone else needs 800Why the 80-year-old fear that testosterone fuels prostate cancer is built on a single flawed 1941 study, and what the androgen saturation model proves insteadHow everyday endocrine disruptors BPA in receipts, phthalates in personal care, atrazine in tap water quietly lower your testosterone even when you eat clean and train hardThe correct AUA testing protocol your doctor may be skipping: two early-morning, fasted measurements plus actual symptoms, not one afternoon blood drawUnderstanding how your own body uses testosterone lets you walk into your doctor's office armed with facts instead of frustration and stop being told you're "fine" when you don't feel it.Thank you to our sponsors:OneSkin - Get 15% off at https://bit.ly/4ekX9gt with code DRLYONExplore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction00:55 - Why one reference range fails everyone01:45 - Men with normal labs who feel terrible02:40 - Dismantling the prostate cancer myth ahead03:40 - Testosterone decline by age data04:30 - It's comorbidities and environment, not just age05:10 - Endocrine disruptors and how they work06:30 - How EDCs lower testosterone08:00 - Common offenders and where they hide09:00 - Receipts, atrazine, and performance apparel10:30 - Reducing your chemical exposure11:45 - The prostate cancer paradigm shift12:20 - The flawed 1941 study13:00 - The androgen saturation model14:00 - Testosterone therapy with prostate cancer data15:00 - What happens when you block androgens15:45 - Androgens and brain protection16:45 - CAG repeats and genetic variability18:30 - The rain and buckets analogy19:30 - AUA testing and diagnosis protocol21:00 - Symptoms, targets, and safe monitoring22:15 - Muscle-centric application and recapIf you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Is the Protein RDA Too Low for You? What 40 Years of Studies Show - Dr. Don Layman & Dr. Heather Leidy | GLS #214

The July Forever Strong Foundations Challenge begins July 6, 2026. This 4-week challenge is designed to help you build a stronger, more energized you through sustainable nutrition, training, and lifestyle habits. Register here: https://bit.ly/4gCmoNR For 40 years you've been told 0.8 grams of protein per kilogram is "enough" but the scientists who contributed the reports behind the new 2025–2030 Dietary Guidelines say not a single study has ever shown that number beats eating more.In this episode, Dr. Gabrielle Lyon sits down with Dr. Don Layman and Dr. Heather Leidy, the protein researchers who developed the scientific reports informing the new U.S. Dietary Guidelines, to discuss:Why the guidelines reprioritized protein to a healthy range of 1.2–1.6 g/kg and why that still isn't technically "high protein"Why you don't really have a protein requirement, but an essential amino acid requirement and what that means for your brain, mood, and antioxidant productionWho's quietly falling short: roughly 20% of women over 60 sit below the RDA, and adolescent girls are among the most consistently deficientHow to spot real protein on a label (Layman's 10-gram threshold) and why most "+protein" snacks are just fairy dustWhat a higher-protein breakfast does to afternoon cravings, backed by fMRI brain-reward dataWalk away knowing how much protein you actually need, why "enough to avoid deficiency" and "enough to thrive" are two different numbers, and how to build every meal around protein first so you're covered on the nutrients that matter most.Thank you to our sponsors:OneSkin - Get 15% off at https://bit.ly/4ekX9gt with code DRLYONExplore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Donald K. Layman at:Website: https://www.metabolictransformation.com/Instagram: https://www.instagram.com/layman.donConnect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction02:00 - The biggest change in 45 years03:36 - Why the guidelines are so controversial06:09 - Process complaints vs. the science08:25 - Protein was always there, just hidden10:26 - Is 1.6g really high protein?13:00 - Half of people are below average13:45 - The randomized trials that say no benefit16:57 - Why cherry-picked studies mislead18:42 - Amino acids are essential, fiber isn't21:17 - Does protein only matter with lifting?33:33 - Nitrogen balance and its blind spot40:02 - The carbohydrate RDA everyone ignores47:37 - The nine essential amino acids49:49 - Why aging makes deficiency worse53:36 - Going below 50% animal protein58:25 - Protein quality and carbohydrate dilution1:04:34 - Hitting protein when you're small1:08:53 - High-protein breakfast and the teen brain1:10:19 - fMRI: blunted food cravings1:18:40 - The saturated fat sticking point1:26:30 - The 10% number from thin air1:40:17 - Is protein in everything fairy dust?1:46:42 - Smart high-protein snacksIf you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Nobody Tells You What GLP-1s Do to Your Sex Drive | GLS #213

The receptor that switches off your appetite on a GLP-1 drug is the same one wired into your reward circuitry, your hormones, and your blood vessels, which means when you turn down hunger, something else may be getting turned down too, and for most people taking these drugs, nobody ever checked.In this solo episode, Dr. Gabrielle Lyon discusses:Why the same drug class can improve sexual function in men with obesity while potentially dampening it in lean or postmenopausal women — and why the deciding factor isn't the drug, it's the bodyHow rapid weight loss raises SHBG, the protein that soaks up free testosterone, so a "normal" total testosterone result can hide a real deficit your bloodwork won't flagWhy women make up 60–70% of GLP-1 prescriptions yet the entire evidence base for female sexual function is two case reports, with zero validated questionnaires in any pivotal trialThe three-tier action plan for anyone on or about to start a GLP-1 — baseline your sexual function first, get free testosterone tested, and protect muscle with protein and resistance trainingWhether you're on a GLP-1 drug or considering one, you'll walk away knowing exactly what to measure before you start and what to watch for after — so a change in your sexual health gets caught as the vital sign it is, instead of being quietly dismissed.Thank you to our sponsors:Cozy Earth - Go to https://bit.ly/44qcXtu for up to 20% off! Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/3QEpYMX or find yours in store at https://bit.ly/3SGAEv3 .Kettle & Fire - Head to https://bit.ly/4oJokGu and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction01:30 - The 35-year-old patient case04:00 - The question: harm or help?05:00 - The case against: the 4.5x ED study06:30 - FAERS database and 182 reports08:00 - Reward circuits, blood flow, and SHBG11:00 - Women are 70%, the data is two case reports12:30 - The case for: detection bias explained15:00 - Validated studies show testosterone rising17:00 - GLP-1 vs testosterone therapy and fertility19:00 - Same receptor, different body22:00 - Cross-examination: holes in both sides26:00 - Why the drugs may not all be the same30:00 - Confidence levels: what Lyon actually believes33:00 - Tier 1: baseline, hormones, protein, training35:00 - Tier 2 and 3: dose, molecule switch, adjuncts36:30 - Your sexuality is a vital sign If you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.