View the Show Notes Page for This Episode
Become a Member to Receive Exclusive Content
Sign Up to Receive Peter’s Weekly Newsletter
Alex Aravanis is a leader in research and development of technologies and clinical tests utilizing the latest tools in DNA analysis and data science. In this episode, Alex delves into two interconnected topics: liquid biopsies and epigenetics. He begins by tracing the trajectory of genome sequencing and tumor sequencing, setting the stage for a detailed exploration of liquid biopsies as an early cancer detection method. The discussion encompasses key concepts such as cell-free DNA, DNA methylation, sensitivity, specificity, and the predictive values associated with liquid biopsies. Transitioning to epigenetics, Alex examines the intricate interplay of DNA methylation and aging biology and explores the possibility of using cellular reprogramming to reverse epigenetic changes that occur with aging.
We discuss:
Connect With Peter on Twitter, Instagram, Facebook and YouTube
#76 - Kyle Kingsbury: Finding meaning, depression, and psychedelics
Qualy #43 - What are Peter’s thoughts on fasting and ketosis for females?
#75 - David Light: Zantac recall due to cancer concerns – what you need to know
Qualy #38 - Finding meaning in struggle and why we are less happy than ever (David Foster Wallace)
#74 – Jason Fried: Optimizing efficiency and work-life balance
Qualy #33 - How silent bravado and incessant striving can lead to a functional (and actual) death, and why Paul is critical of the current state of psychiatry
#73 - AMA #9: NAD & metformin, fat-burning zone, creatine, estrogenization of men, emergency kit for cold & flu, and more
#72 - Dan Harris: 10% happier – meditation, kindness, and compassion
Qualy #26 - What is Peter looking to achieve and monitor with his blood glucose monitor?
#71 - Katherine Eban: Widespread fraud in the generic drug industry
Qualy #24 - What are the “ABCs” of Alzheimer’s prevention?
#70 - David Sinclair, Ph.D.: How cellular reprogramming could slow our aging clock (and the latest research on NAD)
Qualy #19 - A unifying theory of aging
#69 - Ronesh Sinha, M.D.: Insights into the manifestation of metabolic disease in a patient population predisposed to metabolic syndrome, and what it teaches us more broadly
Qualy #16 - How much does cognitive activity ward off cognitive decline?
#68 - Marty Makary, M.D.: The US healthcare system—why it’s broken, steps to fix it, and how to protect yourself
Qualy #9 - The importance of exercise for brain health
#67 - AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more
Qualy #6 - What are the best lab tests to request specifically for longevity
#66 - Vamsi Mootha, M.D.: Aging, type 2 diabetes, cancer, Alzheimer’s disease, and Parkinson’s disease – do all roads lead to mitochondria?
Create your
podcast in
minutes
It is Free
Good Mood Revolution
Huberman Lab
Good Nurse Bad Nurse
The Relaxback UK Show
On Call With Dr. Anselm Anyoha
The Doctor’s Farmacy with Mark Hyman, M.D.