David Andrew Sinclair, PhD is an Australian biologist and professor of genetics. He is also a co-director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, and is known for his research on aging with a focus on epigenetics.
Time Stamps:
0:35:27 Podcast begins with David Sinclair
0:36:25 Is when we eat more important than what we eat?
0:38:45 What is the connection between time restrictive eating and longevity?
0:43:54 What causes us to age?
0:45:46 Epigenetic change.
0:52:03 What causes DNA breaks?
0:55:28 What plant foods create DNA breaks?
0:57:13 PARP enzymes
1:00:46 Where does NAD come from? How do we make it? What enzymes use it?
1:04:50 NAD recycling pathway.
1:12:13 Sirtuins.
1:24:14 What are the other longevity genes? (AMP kinase and mTOR) How are they connected to sirtuins?
1:31:50 Does being in a ketogenic state increase NAD?
1:40:30 Xenohormesis and plant molecules.
1:45:50 Resveratrol trials.
1:51:55 mTOR.
1:57:25 David’s thoughts on animal protein.
2:04:03 Meat consumption in relation to the environment and regenerative agriculture.
2:11:28 Where to find David Sinclair.
David’s info:
https://genetics.med.harvard.edu/sinc...
https://lifespanbook.com/
Instagram: @davidsinclairphd
Twitter: @davidasinclair
Sponsors:
Heart & Soil: www.heartandsoil.co
White Oak Pastures: www.Whiteoakpastures.com, use code: CarnivoreMD for 10% off your first order
The Cold Plunge: TheColdPlunge.com, use code CarnivoreMD for $111 off your cold plunge
Eight Sleep: https://www.eightsleep.com/carnivoremd use code “CARNIVOREMD” to save $150
Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt
189. Keto vs Animal-Based, a friendly debate with Ken Berry, MD
188. How seed oils make you fat with Tucker Goodrich and Jeff Nobbs
187. Meat vs. plants for longevity
186. Dr. Tommy Wood: Tools to Keep Your Brain Healthy and Avoid Dementia
185. How to reverse diabetes
184. The problem with eating plants
183. Is big pharma corrupt with John Abramson
182. Does red meat cause cancer?
181. How to reverse high blood pressure
180. How to lose weight
179. Am I on TRT? August 2022 bloodwork update
178. Statins: Should you take one for “elevated” LDL?
177. Glyphosate: how it's harming you
176. Danica Patrick: Breast implants ruined her health
175. AMA: Glyphosate, Sunning your balls, and APOE4
174. AMA: Randle cycle, Fruit and NAFLD, Contaminated Avocado oil/Olive oil, PFAs, Deer liver and Pregnancy
173. Animal Based Vs Keto, A friendly debate with Thomas DeLauer
172. Dangers of a keto diet
171. July 2022 Bloodwork Review!
170. How to fix your gut!
Create your
podcast in
minutes
It is Free
Good Mood Revolution
Good Nurse Bad Nurse
The Relaxback UK Show
On Call With Dr. Anselm Anyoha
The Doctor’s Farmacy with Mark Hyman, M.D.
The Peter Attia Drive