Phage therapy has gained a lot of traction but the challenges created by this approach have not been properly assessed at a big scale. We often read about therapy successes on isolated cases but, rarely, we read or hear about failures. AAC recently published a case series of patients who failed phage therapy. Today, we will discuss this topic with the principal investigator on the research.
Topics discussed:Pseudomonas aeruginosa ventricular assist device infections: findings from ineffective phage therapies in five cases https://journals.asm.org/doi/10.1128/aac.01728-23
Questions Answered:This episode is brought to you by the Antimicrobial Agents and Chemotherapy journal available at aac.asm.org. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit asm.org/membership to sign up.
Visit journals.asm.org/journal/aac to browse issues and/or submit a manuscript.
Phages as Therapeutic Tools Against Multidrug Resistant Bacteria (AAC ed.)
COVID-19 Associated Pulmonary Aspergillosis - The Other CAPA (JCM ed.)
WHO Critical Review of the Antibacterial Pipeline (AAC ed.)
Testing for COVID-19 During the Age of Omicron (JCM ed.)
Best Clinical Microbiology Papers of 2021 (JCM ed.)
Treatment of Acinetobacter spp. Infections (AAC ed.)
SARS-CoV-2 Sequencing for Clinical Care and Infection Control (JCM ed.)
Candida auris at the Intersection of the COVID-19 Pandemic (AAC ed.)
COVID-19 Testing - Schools, False Positives, and In-Person Meetings (JCM ed.)
Testing for COVID-19 Infectivity (JCM ed.)
Treatment of VRE Infections (AAC ed.)
Advances in Serologic Testing for COVID-19 (JCM ed.)
Innovative Clinical Trials for COVID-19 (AAC ed.)
Mythbusting in Susceptibility Testing (JCM ed.)
Antimalarial Drug-Resistance (AAC ed.)
Staphylococcus argenteus: another coagulase positive Staphylococcus (JCM ed.)
β-lactam/β-lactamase inhibitor combinations (AAC ed.)
Reconciling Genotypic and Phenotypic Susceptibility Tests (JCM ed.)
Gaps in Laboratory Diagnosis of Fungal Diseases (JCM ed.)
Pandemic Built Environment (mSystems ed.)
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