Patrick Radden Keefe is an award-winning staff writer at The New Yorker and the bestselling author of Empire of Pain: The Secret History of the Sackler Dynasty. In this episode, Patrick tells the story of the Sackler family and Purdue Pharma - makers of the pain management drug OxyContin, providing the backdrop for the ensuing opioid epidemic and public health crisis. He reveals the implicit and sometimes explicit corruption of all parties involved in the development, approval, and marketing of OxyContin, leading to a cascade of unintended consequences including addiction and death. He explains the unfortunate lack of accountability for the current crisis, as well as what it all means for those with legitimate pain management needs. Finally, he examines the difficult path ahead towards finding a solution.
We discuss:
#137 - Paul Offit, M.D.: An expert perspective on COVID-19 vaccines
#136 - AMA #17: Body composition methods tour de force, insulin resistance, and Topo Chico
#135 - BJ Miller, M.D.: How understanding death leads to a better life
#134 - James O’Keefe, M.D.: Preventing cardiovascular disease and the risk of too much exercise.
#133 - Vinay Prasad, M.D., M.P.H: Hallmarks of successful cancer policy
#132 - AMA #16: Exploring hot and cold therapy
#131 - Beth Lewis: The Art of Stability: Learning about pain, mitigating injury, and moving better through life
#130 - Carol Tavris, Ph.D. & Elliot Aronson, Ph.D.: Recognizing and overcoming cognitive dissonance
#129 - Tom Dayspring, M.D.: The latest insights into cardiovascular disease and lipidology
#128 – Irene Davis, Ph.D.: The evolution of the foot, running injuries, and minimalist shoes
#127 - AMA #3 with sleep expert, Matthew Walker, Ph.D.: Fasting, gut health, blue light, caffeine, REM sleep, and more
#126 – Matthew Walker, Ph.D.: Sleep and immune function, chronotypes, hygiene tips, and addressing questions about his book
#125 - John Arnold: The most prolific philanthropist you may not have heard of
#124 - AMA #15: Real-world case studies—metabolic dysregulation, low testosterone, menopause, and more
#123 - Joan Mannick, M.D. & Nir Barzilai, M.D.: Rapamycin and metformin—longevity, immune enhancement, and COVID-19
#122 - Lori Gottlieb: Understanding pain, therapeutic breakthroughs, and keys to enduring emotional health
#121 - Azra Raza, M.D.: Why we're losing the war on cancer
#120 - AMA with Dom D’Agostino, Ph.D., Part II of II: Ketosis for cancer and chronic disease, hyperbaric oxygen therapy, and the effect of ketosis on female health
#119 - Terry Real: Breaking the cycle of shame, anger, and depression
#118 - Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging
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