Steven Nissen, MD talks with Jerry Estep, MD, Section Head, Heart Failure and Transplantation and Edward Soltesz, MD, Surgical Director of the Kaufman Center for Heart Failure and Recovery about what a diagnosis of heart failure means, what medications help improve survival and quality of life, when a patient should seek a second opinion about advanced heart failure therapies such as left ventricular assist device (LVAD) or heart transplant, and what LVADs do and how they work.