“Depression is the number one reason in the world for disability,” says Audrey Gruss, Founder of Hopefragrances.com and Hopefordepression.org. “Thirty-five percent of people don’t respond to the meds out there.” Gruss, who began her career as the assistant to the Medical Director at the Revlon Research Center, says that since 1985, every medication has been a spinoff of Prozac, which doesn’t work for everyone. One of those who Prozac failed was her mother, Hope, who had struggled with depression since her thirties. “It was called a nervous breakdown,” Gruss says. “It had stigma.” When visiting her mother at the hospital Gruss would ask why there was no cure and why the top companies in the brain science business were not doing research. The answer she got: research “was too expensive and it was too lucrative to simply repurpose drugs.” After her mother passed away in 2005, Gruss, who had spent the majority of her career in the beauty sector working for name brands like Elizabeth Arden and creating the Doral Saturnia Spa in Miami, launched Hope Fragrances to fund her research foundation, Hope For Depression. “We put together a group of leaders in each discipline of neuroscience and cellular biology,” she says. “They are collaborating and sharing research. We are in clinical trials at Columbia University Medical Center and Mount Sinai with a brand new category of medications for people who don’t respond to Prozac.”
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#225 Her Reinvention Took Her from NASA to Podcasting (Izolda Trakhtenberg)
#224 When Healing from Your Childhood Trauma Leads to Radical Self-Awareness (Poonam Bhuchar)
#223 How to Reinvent Yourself as a Writer – and Actually Make Money! (Rebecca Weber)
#222 When Your Reinvention Takes You From Entrepreneurship to the Corporate World (Barbara Viteri)
#221: World Menopause Day: A Special Conversation with Michelle Jacobs (Co-Founder, Womanness)
#220 Reinventing After Reaching the Top of the Mountain (Shelley Paxton)
#219 90% of Entrepreneurs Fail: Why You Should Reinvent Through a Franchise (Kim Daly)
#217 Reinventing from a Stable Career to Fill a Need Gap (Sharon Linder)
#216 From Stay-at-Home Mom to Addiction Recovery Maven (Felicia Montiforte Kleinpeter)
#215 Her Health Crisis Led her to Start a Nonprofit at 27 (Donna Cryer)
#214 When Covid Forces You to Pivot – and You Thrive (Sarah LaFleur)
#213 Reinventing How Women 50+ Are Seen in the Fashion Industry (Stephanie O’Dell)
#212 She Wrote the Guidebook for Midlife Reinvention (Joanne Lipman)
#211 The Secret to a Successful Reinvention (Katie Fogarty)
#210 What to Do When You’re Bored With Your Job (Shilpa Kulshrestha)
#209: He Decided to Start a New Business – Every Year! (Sean Castrina)
#208 Taking Her Reinvention Story to the Stage (LeeAnn Marie Webster)
#208 Reinventing Your Relationship to Uncertainty (Jill Griffin)
#207 My Reinvention Took Me from Poverty to the White House (Rebecca Contreras)
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