“Depression is the number one reason in the world for disability,” says Audrey Gruss, Founder of Hopefragrances.com and Hopefordepression.org. “Thirty-five percent of people don’t respond to the meds out there.” Gruss, who began her career as the assistant to the Medical Director at the Revlon Research Center, says that since 1985, every medication has been a spinoff of Prozac, which doesn’t work for everyone. One of those who Prozac failed was her mother, Hope, who had struggled with depression since her thirties. “It was called a nervous breakdown,” Gruss says. “It had stigma.” When visiting her mother at the hospital Gruss would ask why there was no cure and why the top companies in the brain science business were not doing research. The answer she got: research “was too expensive and it was too lucrative to simply repurpose drugs.” After her mother passed away in 2005, Gruss, who had spent the majority of her career in the beauty sector working for name brands like Elizabeth Arden and creating the Doral Saturnia Spa in Miami, launched Hope Fragrances to fund her research foundation, Hope For Depression. “We put together a group of leaders in each discipline of neuroscience and cellular biology,” she says. “They are collaborating and sharing research. We are in clinical trials at Columbia University Medical Center and Mount Sinai with a brand new category of medications for people who don’t respond to Prozac.”
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#186 Reinventing Yourself After the Worst Year of Your Life (Jane Enright)
#185 The Year That Made Me Rethink Everything (Claudia Dreifus)
#184: How to Connect to What You Really Want (Michael Clinton)
#183 Turning a Personal Passion for Art Into Unique Travel Experiences for Women (Suzanne Randolph)
#182 From The Army to Arming Entrepreneurs for Success (Laura Noel)
#181 Is Your “Perfect” Daughter Hiding Something From You? (Caralena Peterson)
#180 How to Make a Leap in Your Career Reinvention (Dana Hilmer & Wendy Perrotti)
#179 Stop Letting Fear Guide You! (Jessica Joines)
#178 Reinventing Your Creativity as a Luxury Business (Jane Pollak)
#177 Teaching Others How to Deal with their Anger (Doug Noll)
#176 Reinventing Your Job Search in Your 40s, 50, and 60s (Gillian Williams)
#175 When Trauma Forces Your Reinvention (Carrington Smith)
#174 When Injury Leads to Innovation (Ivy Slater)
#173 Helping Women Scale Their Business to $1 Million (Eleanor Beaton)
#172 From Famous Family to Fashion Pioneer (Liz Lange)
#171 Reinventing Yourself All Over Again From Scratch (Kathleen Smith)
#170: Her Reinvention as a Writer Happened at 63 (Stephanie Raffelock)
#169: When an Economic Upheaval Forces You to Reinvent Your Career (Susan Schoenberger)
#168 From Nun to Fortune 500 Founder: How One Woman Overcame Her Fear of Reinvention (Ellen Snee)
#167: Reinventing After 50 to Recover Your Life’s Passion (Jennifer Lewis McKay)
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