How to test for Leaky Gut

Symptoms to Watch For:

• Chronic diarrhea or constipation
• Bloating and gas
• Food sensitivities
• Fatigue
• Skin issues (e.g., eczema)
• Joint pain
• Autoimmune conditions

Testing for leaky gut, also known as increased intestinal permeability, involves several methods. Here are some common approaches:

1. Lactulose-Mannitol Test

This is a urine test that measures the absorption of two non-metabolized sugars: lactulose and mannitol.

• Procedure: The patient drinks a solution containing these sugars. After a few hours, urine is collected and analyzed for the presence of these sugars.
• Interpretation: Higher levels of lactulose and lower levels of mannitol in the urine indicate increased intestinal permeability.

2. Zonulin Test

Zonulin is a protein that modulates the permeability of tight junctions between cells of the digestive tract. Elevated levels of zonulin in blood or stool can indicate leaky gut.

• Procedure: A blood or stool sample is taken and analyzed for zonulin levels.
• Interpretation: Higher levels of zonulin suggest increased intestinal permeability.

3. Intestinal Permeability Assessment

Some tests measure the presence of larger, undigested food particles, toxins, or bacteria in the bloodstream, which should normally be contained within the intestines.

• Procedure: Blood tests for antibodies against these particles can be performed.
• Interpretation: The presence of these antibodies may indicate that these particles are passing through the intestinal lining into the bloodstream.

4. Stool Tests

Comprehensive stool analysis can provide insights into gut health, including inflammation markers, presence of pathogens, and digestive function.

• Procedure: A stool sample is collected and analyzed.
• Interpretation: Results can indicate dysbiosis or inflammation, which may be associated with leaky gut.

5. Food Sensitivity Testing

Leaky gut can sometimes be associated with increased food sensitivities or intolerances.

• Procedure: Blood tests for IgG antibodies against various foods can be done.
• Interpretation: High levels of IgG antibodies to specific foods can suggest increased intestinal permeability allowing food particles to enter the bloodstream.

I discuss leaky gut in many of my online programs, because weight loss becomes VERY problematic due to the inflammation caused (and consquential liver damage) due to leaky gut. 

Would you like to join one of my programs, or are you interested in coaching or brining me into your business?

I would like to hear from you  Jo@theshrinkshop.com