For centuries, Baloch smuggling cartels defied the might three empires, trafficking goods through British India, Persia and Afghanistan. Today, the modern descendants of those cartels are drowning the Indian Ocean in methamphetamine and heroin. Seizures are at record levels—but the deep ties of the traffickers with the ISI, the meltdown of Afghanistan and the cold economic logic of the narcotics market, mean the drug cartels are thriving.