There has been significant debate regarding the safety of achieving very low LDL-C levels, including a potential negative impact on cognitive function. The current ACC/AHA guidelines (circa 2013) suggest decreasing the statin dose in patients with two consecutive LDL-C levels below 40 mg/dL based on expert opinion. The lack of evidence has been a major challenge for clinicians and it is unclear whether medication doses should be reduced in high-risk patients who may benefit from very low LDL-C levels. A recently published meta-analysis sought to address this clinical dilemma.
Podcast Case: Very Low LDL Case
Guest Authors: Apryl Anderson, PharmD and Dave Dixon, PharmD, BCPS, BCACP, CLS, CDE
Music by Good Talk
Addressing the Adherence Problem: Do Med Sync Programs Really Work?
The Importance of a Healthy Mind in Patients with an Unhealthy Heart
Addressing the Concerns and Needs of Transgender Persons
The Power of Pharmacist-to-Pharmacist Handoffs During Transitions of Care
Improving Access to Naloxone - Yes, Pharmacists (Nar)CAN!
Making the GRADE: It’s time to AGREE on better CPGs
If Your Heart’s Not into It, Do You Really Need to Take Your Meds?
Should We Hold Our Breath for Vitamin D in COPD?
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D-PRESCRIBE Study: As Age Goes Up, The Medication Must Go Down!
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Is a Team-Based Approach in Primary Care Worth It?
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Another Case of Newer Isn’t Always Better! Gabapentin vs. Pregabalin for Chronic Sciatica
Fall Risk and Benzos – Is Trazodone Really the Knight in Shining Armor?
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Another Attempt to ARRIVE at an Answer Using Aspirin for Primary Prevention
Does a “One-Size-Fits-All” Aspirin Dosing Approach Still Hold WEIGHT?
Aspirin for Primary Prevention of CV Events in Diabetes - Is the Evidence ASCENDing?
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