The 63rd American Society of Hematology (ASH) annual meeting saw a plethora of updates in lymphoma. While most of them generated a lot of fruitful conversations, some of the breakthroughs have the potential to change practice.
In this roundtable discussion, Graham Collins, MA, MBBS, MRCP, FRCPath, DPhil, Oxford University Hospitals NHS Foundation Trust, Oxford, UK, and Wendy Osborne, MBBS (Hons), MRCP, FRCPath, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK, review the most exciting updates in lymphoma from the 2021 ASH annual meeting and reflect on how the data may impact clinical practice in the UK.
MPN highlights at ASH 2023: novel agents & ongoing clinical trials in ET, PV and MF
iwNHL 2023 Session V: Expanding the CAR platform in NHL
iwCLL 2023: The role of continuous BTKis, approaching Richter’s transformation & addressing the underrepresentation of elderly patients in trials
iwNHL 2023 Session IV: Novel therapies in NHL: BTK inhibitors, BTK degraders, and bispecific antibodies
Unmet needs in AL amyloidosis, novel treatment strategies being explored, and the role of CHIP
iwNHL 2023 Session III: Recent updates with the use of antibody-drug conjugates in NHL
MPN diagnosis & treatment: novel agents in PV, clinical guidance for the use of JAK inhibitors & the growing role of combination approaches
iwNHL 2023 Session II: The evolving treatment landscape in mantle cell lymphoma
iwNHL 2023 Session I: Updates on the biology and treatment of T-cell lymphoma
iwAL 2023 Session IV: transplantation and immunotherapies in AML: improving patient outcomes
Classifying frailty and approaching elderly patients with lymphoma
Updates on the diagnosis, risk stratification and treatment of lower-risk MDS
iwAL 2023 Session III: The relevance of TP53 mutation in AML
iwAL 2023 Session II: Novel treatments in AML: FLT3 inhibitors, combinations, and more
iwAL 2023 Session I: Clonal hematopoiesis in AML, early detection and potential therapeutics
Applications of MRD in multiple myeloma: using MRD to guide treatment decisions
Exploring and comparing the curative potential of CAR-T therapy & bispecific antibodies in R/R DLBCL
Pre-MDS states: improving prognosis, novel therapeutic approaches, and challenges with distinguishing these conditions
Accelerated-phase MPNs: mutational landscape, challenges, and novel treatment strategies being explored
Determining the optimal sequencing of bispecifics and CAR-T cells in multiple myeloma
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