This Week in Pediatric Oncology
Science
April 25, 2011
In this third episode, host Tim Cripe, MD, PhD, asks his co-hosts to discuss two recent papers that provide new information about genetic predisposition to increased toxicity to vincristine in some children, and the results of a phase II study using a combination therapy (irinotecan and temozolomide) in relapsed or refractory neuroblastoma.
1:24 Maureen O'Brien, MD discusses "Increased risk of vincristine neurotoxicity associated with low CYP3A5 expression genotype in children with acute lymphoblastic leukemia" in Pediatr Blood Cancer. 2011 Mar;56(3):361-7. doi: 10.1002/pbc.22845. Epub 2010 Nov 11.http://www.ncbi.nlm.nih.gov/pubmed/21225912
22:10 Lars Wagner, MD discusses "Phase II study of irinotecan and temozolomide in children with relapsed or refractory neuroblastoma: a Children's Oncology Group study" from J Clin Oncol. 2011 Jan 10;29(2):208-13. Epub 2010 Nov 29. http://www.ncbi.nlm.nih.gov/pubmed/21115869
TWiPO #72 - Dr. Eugene Hwang discusses his work with immunotherapy and pseudo-progression
TWiPO #71 - Interview with Nancy Goodman, Founder and Executive Director of Kids v. Cancer
TWiPO #70 - Dr. Joshua Rubin talks about his research done on gender differences to cancer
TWiPO #69 - Dr. Peter Shields talks about the effects of e-cigarettes
TWiPO #68 - Dr. Dean Lee discusses his experience with T-cell CARs
TWiPO #67 - Interview with Dr. Mitchell Cairo
TWIPO #66 - Interview with Dr. Rani George
TWiPO #65 - Interview with Dr. Brenda Weigel
TWiPO #64 - Interview with Dr. Lars Wagner
TWiPO #63 - Dr. Javier Blanco discusses chemotherapy late effects and cardio-toxicity
TWiPO #62 - Interview with Dr. Uri Tabori
TWIPO #61 - Interview with Dr. Matthew Breen
TWIPO #60 - Interview with Dr. Josua Mendell
TWiPo #59 ~ Interview with Dr. Sajid Qureshi
TWiPO #58 ~ Interview with Dr. Damon Reed
TWIPO # 57 Interview with Dr. Elizabeth Lawlor
TWIPO #56 ~ Interview with Dr. Mark Hatley
TWiPO #55 ~ Interview with Dr. Chrystal Louis
TWiPO #54 ~ Interview with Dr. Kim Kramer
TWiPO #53 ~ Interview with Linda McAllister-Lucas
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