DDT Method Podcast

Protocols Over Stacks: What Serious Enhanced Athletes Build Before They Inject

Deep dive into protocols → Join the DDT Method community: https://www.skool.com/ddtmethodHunter Williams and Taylor Williams — two of the most respected coaches in the peptide and performance enhancement space — return to the DDT Method Podcast for a comprehensive deep dive into building intelligent protocols from the ground up. This husband-and-wife coaching duo works with hundreds of men and women, and they bring real-world, anecdotal evidence to every recommendation.This episode covers Hunter's 5-Bucket Protocol Framework (reproductive hormones, growth hormone, thyroid, insulin sensitizers, and mitochondrial support), Taylor's women-specific layering approach, the emerging molecules catching their attention (P21, PE2228, MK-777, injectable bioregulators, transdermal peptides), a full GLP selection guide (tirzepatide vs. retatrutide sequencing), mitochondrial optimization (SS31, MOTC, SLU dosing, ATX as an alternative), the case for SGLT2 inhibitors over metformin, and underrated muscle builders like IGF-1 LR3.CHAPTERS:00:00 The State of the Industry & Peptide Fatigue03:47 Taylor's Nootropic Deep Dive: P21 & PE222807:22 Injectable Bioregulators & Cartilax Results09:54 The Transdermal Peptide Wave12:26 The Problem With Stacking Without a Plan16:37 Hunter's 5-Bucket Protocol Framework19:12 Taylor's Women-Specific Layering Approach22:00 Building the Male Protocol: Bucket by Bucket25:42 MK-777: The Oral GH Secret Nobody Expected30:30 Mid-Roll: DDT Method Skool Community31:27 GLP Selection: Why Tirzepatide Before Retatrutide35:37 Drew's Approach: Pulling One Lever at a Time38:14 Mitochondrial Optimization: SS31 vs. MOTC Sequencing42:20 Taylor's SLU Burnout Story & Recovery47:54 Hunter's SLU Dosing Journey: From 100mcg to 2mg and Back51:09 ATX: The AMPK Activator With Human Trial Data52:59 Metformin, Jardiance & SGLT2 Inhibitors58:16 Drew's HDL Results on 50mg Anavar + Jardiance59:24 Underrated Compounds: ACE-167 & IGF-1 LR31:04:54 Where to Find Hunter & Taylor WilliamsKEY TAKEAWAYS:Hunter's 5-Bucket Framework for building a complete peptide protocol from scratchTaylor's women-specific layering approach and why it differs from what most coaches recommendThe oral GH alternative that rivaled Hunter's injectable protocol — with Oura data to back it upWhy starting with the "best" GLP might actually be the worst move for new usersThe mitochondrial sequencing mistake that's leaving people exhausted instead of energizedTaylor's firsthand experience pushing SLU too high — and what it did to her nervous systemThe AMPK activator with human trial data that delivers SLU-like fat loss without the burnoutThe drug combination that may make metformin obsolete — and the blood work to prove itThe most underrated muscle builder that even experienced athletes keep overlookingA pipeline molecule nobody's talking about yet that could change natural testosteroneCONNECT WITH HUNTER & TAYLOR WILLIAMS:Hunter's Website: https://hunterwilliamshealth.comHunter's YouTube: Hunter Williams PodcastTaylor's YouTube: Taylor Williams PeptidesInstagram: @hunterwilliamscoaching / @taylorwilliamscoaching

The Training System That Builds Complete Athletes | Josh Settlage

Join the DDT Method community for exclusive deep dives on PEDs, peptides and biohacking protocols: https://www.skool.com/ddt-methodJosh Settlage is a strength and conditioning coach specializing in grappling and combat sports athletes. A protege of Mark Bell, Josh spent years learning at Super Training Gym before building The Strength Matrix -- his coaching practice dedicated to helping grapplers lift heavy and roll hard.In this episode, Drew and Josh break down why being "jacked in all areas of conditioning" matters the most to being a well rounded athlete. They cover the three energy systems you MUST train, why the "no cardio" flex is actually holding back your gains, how to apply conjugate training methods for any goal (not just powerlifting), the truth about HIIT misconceptions, and performance-enhancing compounds like DADA, BAM-15, L-carnitine, ITPP, and injectable glutathione for conditioning and recovery.Key Takeaways:Being conditioned across all energy systems (ATP-phosphocreatine, fast glycolysis, aerobic) is the mark of a complete athleteBuilding your aerobic base helps you recover faster between strength sessions and add more training volumeTrue HIIT uses a 1:3 work-to-rest ratio at 15-30 seconds of real intensity -- not 40 minutes of moderate effortThe VIP Method (Vision, Intention, Purpose) is the framework for breaking through training plateausDADA increases ATP yield from glucose (more performance); BAM-15 decreases ATP efficiency (more fat burning) -- never combine on the same dayCondensed conjugate (max effort + dynamic effort + repetition effort) in a 3-day split builds muscle without sacrificing explosiveness or conditioningInjectable L-carnitine is glycogen-sparing and helps sustain energy in long training sessionsInjectable glutathione used every 2-3 weeks acts as a "fire extinguisher" for accumulated oxidative stressWhen people say they follow their diet 80/20, it's really more like 50/50 -- push to 90/10 for 12 weeks and see what happensConnect with Josh Settlage:YouTube: @JoshSettlageInstagram: @JoshSettlageCoaching: https://thestrengthmatrix.comConnect with Drew Donaldson:YouTube: @DDTMethodInstagram: @DDTMethod

The Peptide Mistakes Enhanced Athletes Are Still Making in 2026

Join the DDT Method community → https://www.skool.com/ddtmethodMike White (@mike.ryan.white) is a PhD Candidate in Clinical Physiology, former D1 Strength & Conditioning Coach, and coach to enhanced athletes who believe health management should be as rigorous as training programming. In this episode, Mike breaks down the real ceiling on SLU-PP-332 dosing (he ran 500mg/day to find it), why telmisartan is more than a blood pressure drug, the GLP-1 debate that's splitting the coaching world, and why "chicken and rice coaching" is failing athletes when it matters most.Drew and Mike go deep on peptide periodization, mitochondrial health strategy, retatrutide's underrated fat loss mechanisms, the overlooked power of LL-37 for gut health, and how to use DNP responsibly on rest days. This is protocol-level conversation for athletes who are done guessing.Chapters:0:00 - The Craziest Cycles Ever Run3:35 - Who Is Mike White?9:06 - What Is a "Chicken and Rice Coach"?14:06 - Common Health Issues in Men & Women21:15 - Drew's Personal Health Stack22:54 - Optimizing Health on TRT Plus24:46 - Cardio Programming for Every Client26:22 - Training Philosophy: Low Volume vs. High Volume31:15 - SLU-PP-332: From 250mcg to 500mg36:13 - Understanding SS-31 & Mitochondrial Peptides39:07 - Biggest Peptide Mistakes People Make41:53 - GLP-1s Are Not Cheating49:53 - Underrated PEDs, Peptides & Supplements54:40 - Sodium, Potassium & Electrolyte Balance1:00:11 - Hidden Gems: LL-37 & DNP1:05:41 - Where to Find Mike WhiteKey Takeaways:SLU-PP-332 has an effective ceiling at ~100mg — at 500mg, Mike experienced DNP-like heat and metabolic dysfunction with no additional benefitTelmisartan up to 320mg/day offers benefits beyond blood pressure: PPAR gamma activation, brain health, cardiac remodeling, and renal protectionGLP-1s are not cheating — 1 in 8 adults is currently on one, with benefits including lipid oxidation, neural inflammation reduction, and insulin sensitizationRetatrutide is one of the few fat loss tools that enhances both lipolysis and beta oxidation simultaneouslyLL-37 for GI health is massively underutilized — gut dysfunction creates a bottleneck for muscle gain, fat loss, and cognitive functionDNP at low, intermittent doses (rest days only) is a legitimate tool when given the respect it requires"More is not better. Better is better." — applies to peptides, training, and every protocol decisionConnect with Mike White:Instagram: @mike.ryan.whiteCoaching Education Cohort: May 1st — DM Mike on InstagramGray Matter MD Clinic: Launching Q2 2026 — TRT & hormone optimization in all 50 statesConnect with Drew Donaldson:DDT Method Skool Group: https://www.skool.com/ddtmethodInstagram: @ddtmethod#peptides #SLU332 #GLP1 #telmisartan #retatrutide #DNP #bodybuilding #enhancedathlete #PEDs #mitochondrialhealth #DDTMethod #MikeWhite #bloodpressure #fatloss #musclegain #LL37 #biohacking

The 3-Part System to Fix Your Gut, Metabolism, and Physique

For the science nerds → Advanced biohacking research: https://www.skool.com/ddtmethodIn this episode of the DDT Method Podcast, Drew Donaldson sits down with coach Paul Romczak to break down the GMT Method—a gut–mitochondria–training framework that fixes the broken foundations behind most peptide and PED abuse. They reveal why stomach acid, butyrate production, metabolic health, and carb cycling matter more for long‑term hypertrophy than stacking the latest GLP‑1 or mitochondrial peptide. If you’re a 29–45‑year‑old lifter on TRT who wants to be cartoon‑character jacked and live a long time, this is your roadmap.CHAPTERS:0:00 Why Peptides Aren’t Fixing Your Broken Foundations3:12 The GMT Method Explained: Gut → Mito → Training8:45 The “Skinny Biohacker vs. Bloated Bodybuilder” Problem14:20 Fixing Stomach Acid: The Fastest Gut Health Win19:40 Butyrate, Fiber, and What Leaky Gut Really Is26:05 Metabolic Health 101: Lose the Body Fat First32:30 Carb Cycling for Insulin Sensitivity and Performance38:50 SS‑31, SLU, and 5‑Amino‑1MQ: When Peptides Actually Make Sense46:10 Smart Use of GLP‑1s, Mito Peptides, and Breaks for Resensitization53:40 DNP, Uncouplers, and Why Paul Pushes Hard Early in Prep1:01:15 Clen, Yohimbine, and Old‑School Tools That Still Work

Deep Water: Why Going Deep Into Everything Guarantees Success

High-level biohacking intel: https://www.skool.com/ddtmethodJon Andersen went from being a bullied, overweight kid in special education to becoming an international pro strongman, New Japan Pro-Wrestling star, and IFBB pro bodybuilder -- all without ever holding a traditional job. In this episode of the DDT Method Podcast, Jon breaks down the "Deep Water" mentality that fueled his success across three sports, three seven-figure businesses, and his current approach to peptides, diet, and longevity at 54 years old.KEY TAKEAWAYS:- Why Jon Andersen credits being a "slow learner" as the single greatest gift that built his entire career across three professional sports- The unconventional protein-only diet approach Jon stumbled into 15 years before science validated it -- and why he still uses it today- How the "Deep Water" mentality of accepting failure before you start a set unlocks reps you never knew you had- The specific peptide stack Jon used to completely reverse nerve damage in his dominant arm and eliminate decades of scar tissue- Why Jon believes retatrutide is the one peptide he would choose above all others, and the unexpected mental health benefits he experienced- The two non-negotiable lifestyle habits Jon says matter more than any peptide or supplement protocolCHAPTERS:0:00 Introduction and Jon Andersen's Origin Story2:22 How Being a "Slow Learner" Became His Superpower5:40 The Accidental Protein Diet That Changed Everything9:02 From First Strongman Contest to International Pro13:02 Flipping Real Estate to Fund the Dream16:14 The Deep Water Mentality Explained19:15 Breaking Into Pro Wrestling with a Fake Resume27:44 Earning an IFBB Pro Card at 42 in Two Shows34:01 The 2008 Crash and Rebuilding Everything38:03 Training and Recovery Evolution at 5443:25 Detox Protocols: Glutathione to TUDCA48:34 Peptide Journey: Early Use to Current Stacks54:35 Retatrutide: The One Peptide He'd Pick Above All59:16 ARA-290, TB-500, and Reversing Decades of Damage1:04:17 Where to Find Jon Andersen OnlineEPISODE RESOURCES:Jon Andersen's Social Media:Instagram: https://www.instagram.com/thejonandersenWebsite: https://japrotocols.comCellular Advantage Academy: https://cellularadvantageacademy.comDeep Water Program: https://www.jon-andersen.com/free-deep-water-ebook/