Interspecies Chimerism: Advances, Applications, and Challenges

This episode of The Stem Cell Report will explore the scientific applications, advances, and challenges of interspecies chimeras – organisms consisting of cells from at least two different species. The development of interspecies chimeras, most recently advanced by the discovery of pluripotent stem cells and enhancements in genetic editing, have led to greater understanding of fundamental developmental and biological concepts, insight into evolution, and even the development of potential regenerative approaches for human health. Martin Pera will be joined by Drs. Ori Bar-Nur and Jun Wu, along with Joel Zvick, next generation scientists who are pioneering advances in interspecies chimera research.

Host
Martin Pera, PhD – Editor-in-Chief, Stem Cell Reports and The Jackson Laboratory
Twitter: @martinperaJAX

Guests
Ori Bar-Nur, PhD, ETH Zurich, Switzerland
Joel Zvick, ETH Zurich, Switzerland 
Jun Wu, PhD, UT Southwestern, USA

Supporting Content
Exclusive generation of rat spermatozoa in sterile mice utilizing blastocyst complementation with pluripotent stem cells, Stem Cell Reports, 2022

About Stem Cell Reports
Stem Cell Reports is the Open Access journal of the International Society for Stem Cell Research (ISSCR) for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.
Twitter: @StemCellReports

About ISSCR
With 4,500 members from more than 70 countries, the International Society for Stem Cell Research is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.
Twitter: @ISSCR

Acknowledgements

ISSCR Staff
Keith Alm, Chief Executive Officer
Yvonne Fisher, Managing Editor, Stem Cell Reports
Kym Kilbourne, Director of Media and Strategic Communications
Jack Mosher, Scientific Advisor

Voice Work
Ben Snitkoff

Music
@Konovalov