Episode 270: 269. What is the Harm in Aspirin?
The trial was terminated after 1015 patients with atrial cardiopathy had been randomized to receive either apixaban or aspirin for a mean follow-up of 1.8 years, recurrent stroke rates were identical (40 events per group; 4.4% annualized rate). There were 7 symptomatic intracranial hemorrhages in the aspirin group and none in the apixaban group, though other major hemorrhages occurred at similar rates
Aspirin is not benign and has real risk--
BTW don't give anticoagulation if the patient does not have atrial fib.
https://jamanetwork.com/journals/jama/article-abstract/2814933
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