BONUS: New study looks at APOL1 gene: do you have it?

Some diseases run in the family, when more than one person has the same kind of illness passed down through genes. One of those genes, called APOL1, has variations that are linked to an increased risk for kidney disease, especially in under-resourced communities of color. In today's bonus episode, we discuss how a clinical research study is looking to understand the effect of APOL1 on kidney transplant outcomes from living and deceased donors, and why it's important for you to be part of this research study.

In this episode, you will hear from:

Marva Moxey-Mims, MD, FASN

Dr. Moxey-Mims is Professor of Pediatrics at George Washington University School of Medicine and Chief of the Division of Nephrology at Children’s National Health System, Washington, D.C.  Dr. Moxey-Mims serves as the Study Chair of the APOLLO Steering Committee and Chair of the Publications & Presentation Committee.

Jonah Odim, MD

Dr. Odim is Chief of the Clinical Transplantation Section at the National Institute of Allergy and Infectious Diseases (NIAID). Dr. Odim serves as a representative of the National Institutes of Health (NIH) on the APOLLO Steering Committee and member of the Dissemination Working Group.

Glenda V. Roberts 

Glenda is the Director of External Relations & Patient Engagement for the Center for Dialysis Innovation at the University of Washington Kidney Research Institute.  Glenda serves as a member of the APOLLO Community Advisory Committee, the Recruitment Committee, and the Dissemination Working Group.

Sylvia E. Rosas, MD, MSCE

Dr. Rosas is a nephrologist and epidemiologist at the Joslin Diabetes Center and the Beth Israel Deaconess Medical Center. Sylvia serves as the Principal Investigator of APOLLO Clinical Center 09 (Harvard University) and member of the Dissemination Working Group.

Krista Lentine, MD, PhD, FAST, FAST

Dr. Lentine is Medical Director of Living Donation, Co-Director of Clinical Research, and Mid-America Transplant/Jane A. Beckman Endowed Chair in Transplantation at Saint Louis University (SLU). Krista serves as co-Principal Investigator for APOLLO Clinical Center 03 (Johns Hopkins | SLU), member of the Data, Ancillary Studies, and Publications & Presentation Committees, and chair of the Dissemination Working Group.

Denay Richards

Ms. Richards and her family were born in the Caribbean when her mother was diagnosed with ESRD. They moved to the United States, where her mother was told that she had about 3 months to live. On August 29th, 2000, Denay’s father donated a kidney to her and in 2020 they celebrated their 20 year - “kidneyversary.” As a child, Denay loved helping her mother with the dialysis process, organizing medications, and attending hospital visits. It was this exposure to the medical field that encouraged Denay to pursue a career in surgery. In 2019 she graduated from Princeton University with a degree in Molecular Biology and as of 2021 is an MD/PhD student in a dual degree program with Robert Wood Johnson Medical School and Princeton University. In 2019, she earned a double board qualification as a fitness nutrition specialist and personal trainer under the International Sports Sciences Association. In 2020, Denay was diagnosed with an APOL1 mutation that is more prevalent in the African American community and has been linked to early kidney failure. Denay says that her diagnosis has empowered her to expand education about renal health, fitness/nutrition, and genetic predispositions for kidney failure to the world, especially disenfranchised populations that are at greater risk.

 

Genetics and kidney disease: https://www.kidney.org/atoz/content/genetics-kidney-disease