The first report to capture Dr. Ann Neubert's attention involved a breeder of French bulldogs and Chihuahuas. Over the course of three months, four puppies were born with curious features. Three females had enlarged vulvas, while one male had swollen mammary glands. The apparent cause: exposure to a medication the breeder put on her skin containing the sex hormone estrogen.
Sex hormone drug exposures in pets draw notice in Europe published on Jan. 30, 2024.
Show notes
Study: Hyperöstrogenismus und Hyperandrogenismus bei Hunden und Katzen infolge sekundärer Exposition
Study: A review of adverse events in animals and children after secondary exposure to transdermal hormone-containing medicinal products
Drug safety bulletin: Bulletin zur Arzneimittelsicherheit - Informationen aus BfArM und PEI
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