Following the introduction in English, this podcast interview is presented in Japanese. It is well known that rapid pacing of the heart causes calcium overload and myocardial cell damage in heart failure patients. However, the cellular mechanisms underlying this phenomenon are unknown. Listen as Associate Editor Masafumi Kitakaze interviews lead author Tomoko Ohkusa (Yamaguchi University Graduate School of Medicine) and expert Motoaki Sano (Keio University School of Medicine) about the latest work by Nakashima et al, which explores rapid electrical stimulation and adhesion gap junctions in cardiomyocytes. Does beta-Catenin play an important role in the formation and stability of gap junctions? Could beta-Catenin signaling pathways form the basis of new cellular therapies to modulate intracellular junction remodeling? Listen to find out.
Tadamitsu Nakashima, Tomoko Ohkusa, Yoko Okamoto, Masaaki Yoshida, Jong-Kook Lee, Yoichi Mizukami, Masafumi Yano Rapid electrical stimulation causes alterations in cardiac intercellular junction proteins of cardiomyocytes Am J Physiol Heart Circ Physiol, published online Articles in Press March 7, 2014; published in May 1, 2014 issue. DOI: 10.1152/ajpheart.00653.2013.
More Episodes
2023-07-31
426
2023-07-24
351
2023-06-27
269
2023-04-10
437
2023-03-28
504
2023-02-28
463
2023-02-10
474
2023-02-07
403
2022-12-22
682
2022-12-15
318
2022-11-17
455
2022-11-04
307
2022-10-04
376
2022-09-14
371
2022-09-01
322
2022-08-02
409
2022-07-25
291
Get this podcast on your
phone, FREE
