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About This Episode:
In 1959 a landmark clinical trial, often referred to as the LA Veterans Study, began with the aim to investigate the effects of replacing dietary saturated fats with polyunsaturated fats, on the progression of atherosclerosis and cardiovascular outcomes.
This was an eight-year clinical trial in 846 domiciled male veterans in the US. The diets between the control and experimental groups differed by saturated fat and polyunsaturated fat (particularly linoleic acid) content, but were similar in calories and total dietary fat.
The findings of the study suggested that replacing saturated fat with polyunsaturated fat was beneficial for reducing heart disease risk. However, the study also reported an unexpected increase in non-cardiac mortality in the intervention group, which raised concerns.
In this episode, we discuss why the LA Veterans Study was such a seminal trial and what we can learn from it.
#521: How Does Coffee Impact Our Health?
#520: How Exercise Impacts Appetite, Food Intake and Adiposity – James Dorling, PhD
SNP28: How To Eat for Longevity
#519: Eating Disorders: Inpatient Treatment & Challenges – Helen West, RD
#518: Nutritional Geometry, Philosophy of Science & A Case for Reductionism – Prof. David Raubenheimer & Jonathan Sholl, PhD
#517: Reflecting on Ten Years of Lessons
#516: How to Read Nutrition Studies (Become Confident in Critically Appraising Research)
AMA: Do Low-carbers Need Less Vitmain C? Does Omega-3 Supplementation Actually Benefit Us? & More (SNP 27)
#515: Does Dietary Fat Quality Causally Affect Atherosclerosis Risk? – Jacob Christensen, PhD
#514: Plant-derived Fatty Acids – Ella Baker, PhD
#513: Kidney Stones & Diet – Deepa Kariyawasam, RD
What are Dietary Reference Intakes? Origins, Development & Use (SNP 26)
#512: Alzheimer’s Disease – Drs. Ayesha & Dean Sherzai
#511: Null By Design – When “No Effect” Doesn’t Mean No Effect
#510: Social Comparison: Evidence on its Impacts & What We Can Do – Shannon Beer
AMA: Coconut Oil, Raw Oats, Collagen, & More! (SNP 25)
#509: Helping Clients & Patients Overcome Nutrition Confusion – Jono Steedman, APD
#508: Why Athletes Can Achieve High Performance During an Energy Deficit – Jose Areta, PhD
#507: Does a Higher Portfolio Diet Score Reduce Heart Disease? – Andrea Glenn, PhD
Listener Q&A: Homocysteine, MUFA, Healhty BMI, and more! (Preview)
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