Scientific Sense ® by Gill Eapen: Prof Trey Ideker is Professor of Medicine, Bioengineering and Computer Science at the University of California, San Diego. He directs the National Resource for Network Biology, and the Cancer Cell Map and Psychiatric Cell Map Initiatives.
A multi-scale map of cell structure fusing protein images and interactions. Nature. 2021 Nov 24. doi: 10.1038/s41586-021-04115 “We Might Not Know Half of What’s in Our Cells, New AI Technique Reveals Interpretation of cancer mutations using a multiscale map of protein systems. Science. 2021 A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity. A protein interaction landscape of breast cancer. Science. 2021 Oct;374(6563):eabf3066 “Studies Delve Deep into the Protein Machinery of Cancer Cells.” NCI (4 Nov 2021) “From COVID to cancer, gene-mapping tool could ‘revolutionize’ treatment“. SF Chronicle (2 Oc “Moonshot Project Aims to Understand and Beat Cancer Using Protein Maps“. Singularity Hub (5 Oct 2021) “Looking Beyond DNA to See Cancer with New Clarity,” Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. Cancer Cell (2020), https://doi.org/10.1016/j.ccell.2020.09.014. PMID: 33096023. [PDF] [PubMed] Related Press: UCSD Health, AZoLifeSciences, Med India, Health IT Analytics and ScienceDaily. Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome. Cell Systems. 2020 Aug 26;11(2):176-185.e6. doi: 10.1016/j.cels.2020.06.006. Epub 2020 Jul 2. PMID: 32619550 [PDF] [PubMed] *Cover Article Related Press: Here’s a better way to convert dog years to human years, scientists say. Science Magazine (15 Nov 2019). See also: Scientific American, BBC, NPR, Washington Post, Discover Magazine, Smithsonian, New York Post, (and more) Identifying Epistasis in Cancer Genomes: A Delicate Affair. Cell. 2019 May 30;177(6):1375-1383. doi: 10.1016/j.cell.2019.05.005. Review. PMID: 31150618 [PDF] [PubMed] Using deep learning to model the hierarchical structure and function of a cell.* Nat Methods. 2018 Mar 5. doi: 10.1038/nmeth.4627. PMID: 29505029 [PDF] [PubMed] [Cover Art] *Cover article Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1
--- Send in a voice message: https://podcasters.spotify.com/pod/show/scientificsense/message Support this podcast: https://podcasters.spotify.com/pod/show/scientificsense/supportDr. Ian Williams on Various Topics
Prof. Ellen Armour of Vanderbilt University on Seeing is Believing
Dr. Julio Guerrero, CEO and founder of Cambridge Research and Technology on Energy Technologies
Prof. Julia Lane from NYU on AI policy
Prof. Ayelet Fishbach of the University of Chicago on the science of motivation
Prof. Holden Thorp is Chief Editor Science on Covid, Misinformation, JWST and discrimination
Prof. Leah Krubitzer of University of California, Davis on the future of the brain.
Prof. Alessandro Gavazza of London School of Economics on mortgages, cars and market friction
Prof. Adriana Lleras-Muney of UCLA on the relationships between socio-economic status and health
Prof. Louise Westling of the University of Oregon on Deep History and the Rhythm of Catastrophe
Prof. Benedict C. Albensi of Nova SouthEastern University on Nuclear Factor Kappa B and Mitochondria
Prof. Donna Ginther of the University of Kansas on biases in academic and research decisions
Prof. Bonnie Firestein of Rutgers University on Cypin and Brain Injury
Prof. Priscilla Wald of Duke Univ. on how genomics is rewriting race, medicine and human history
Dr. Marcela Uliano-Silva of the Wellcome Sanger Institute on error-free genome assemblies
Dr. Iain McDonald of the Open University & Univ. of Manchester on Rogue exoplanets
Prof. Timothy Cernak of the Univ of Michigan on supply chains, antivirals and molecular sonification
Prof. Paul Novosad of Dartmouth College on Developing Country Policies.
Prof. Dean Karlan of Northwestern University on Poverty, Mental Health, Borrowing and Interventions.
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