Scientific Sense ® by Gill Eapen: Prof Trey Ideker is Professor of Medicine, Bioengineering and Computer Science at the University of California, San Diego. He directs the National Resource for Network Biology, and the Cancer Cell Map and Psychiatric Cell Map Initiatives.
A multi-scale map of cell structure fusing protein images and interactions. Nature. 2021 Nov 24. doi: 10.1038/s41586-021-04115 “We Might Not Know Half of What’s in Our Cells, New AI Technique Reveals Interpretation of cancer mutations using a multiscale map of protein systems. Science. 2021 A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity. A protein interaction landscape of breast cancer. Science. 2021 Oct;374(6563):eabf3066 “Studies Delve Deep into the Protein Machinery of Cancer Cells.” NCI (4 Nov 2021) “From COVID to cancer, gene-mapping tool could ‘revolutionize’ treatment“. SF Chronicle (2 Oc “Moonshot Project Aims to Understand and Beat Cancer Using Protein Maps“. Singularity Hub (5 Oct 2021) “Looking Beyond DNA to See Cancer with New Clarity,” Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. Cancer Cell (2020), https://doi.org/10.1016/j.ccell.2020.09.014. PMID: 33096023. [PDF] [PubMed] Related Press: UCSD Health, AZoLifeSciences, Med India, Health IT Analytics and ScienceDaily. Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome. Cell Systems. 2020 Aug 26;11(2):176-185.e6. doi: 10.1016/j.cels.2020.06.006. Epub 2020 Jul 2. PMID: 32619550 [PDF] [PubMed] *Cover Article Related Press: Here’s a better way to convert dog years to human years, scientists say. Science Magazine (15 Nov 2019). See also: Scientific American, BBC, NPR, Washington Post, Discover Magazine, Smithsonian, New York Post, (and more) Identifying Epistasis in Cancer Genomes: A Delicate Affair. Cell. 2019 May 30;177(6):1375-1383. doi: 10.1016/j.cell.2019.05.005. Review. PMID: 31150618 [PDF] [PubMed] Using deep learning to model the hierarchical structure and function of a cell.* Nat Methods. 2018 Mar 5. doi: 10.1038/nmeth.4627. PMID: 29505029 [PDF] [PubMed] [Cover Art] *Cover article Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1
--- Send in a voice message: https://podcasters.spotify.com/pod/show/scientificsense/message Support this podcast: https://podcasters.spotify.com/pod/show/scientificsense/supportProf. Susan Goldin-Meadow of the University of Chicago on gestures
Prof. Jörg Rocholl is the president of ESMT, Berlin on political corporate boards and firm value
Prof. Ulrike Malmendier iof the University of California, Berkeley on behavior and decision-making
Prof. Johanna Drucker of UCLA on the Ethics of Aesthetics and Alphabet Histories
Prof. Maria-Luisa Alegre of the University of Chicago on Organ Transplant Rejection
Prof. Azra Raza of Columbia University on Cancer diagnosis, prevention and treatment
Prof. Nathalie Mathieu-Bolh of University of Vermont on the economics of obesity, food and policy
Prof. Philip Lebel of Montclair State University on risk, economic growth and policy
Prof. Frank Wilczek of MIT and the 2004 Nobel Laureate in Physics on the Fundamentals of Physics
Prof. Nadine Strossen of New York Law School on free speech and cancel culture
Prof. Alex Frangi of the University of Leeds on in-silico clinical trials
Prof. Jennifer Jordan of IMD, Switzerland on leadership
Prof. Bruce Hammock of University of California, Davis on insect Biology and Mammalian Enzomology
Prof. Deirdre McCloskey of the University of Illinois at Chicago on Libertarianism and Economics
Prof. Kenneth Pomeranz of the University of Chicago on China, Europe, and the making of the modern World economy
Prof. Claudia Flores of the University of Chicago on aligning law enforcement with human rights
Prof. Holly Ingraham of UCSF on Estrogen signaling in the brain and gut
Prof. Wendy Pearlman of Northwestern University on Syrian uprising and politics
Prof. Sreekumar Bhaskaran of Southern Methodist University on durable goods pricing & distribution
Prof. Marianna Bolognesi of the University of Bologna on language, concepts and communication.
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