In this Episode of the Epigenetics Podcast our guest Lucy Stead from the University of Leeds provides insight into her work on intratumor heterogeneity in Glioblastoma. In order to tackle this area she uses an holistic approach including Computational Genomics, In silico Modeling and Functional Genomics in order to test whether treatment-resistant subclones emerge in recurrent tumors, and characterize them in clinically relevant ways in multiple patients. And this is just a glimpse of what is discussed in this Episode.
References
Contact
The Role of Non-Histone Proteins in Chromosome Structure and Function During Mitosis (Bill Earnshaw)
Effects of DNA Methylation on Chromatin Structure and Transcription (Dirk Schübeler)
CpG Islands, DNA Methylation, and Disease (Adrian Bird)
Biophysical Modeling of 3-D Genome Organization (Leonid Mirny)
From Nucleosome Structure to Function (Karolin Luger)
Identification of Functional Elements in the Genome (Bing Ren)
Hi-C and Three-Dimensional Genome Sequencing (Erez Lieberman Aiden)
Chromatin Structure and Dynamics at Ribosomal RNA Genes (Tom Moss)
Epigenetic Origins Of Heterogeneity And Disease (Andrew Pospisilik)
PIXUL: On the Leading Edge of Chromatin Shearing (Karol Bomsztyk and Tom Matula)
Influence of Histone Variants on Chromatin Structure and Metabolism (Markus Buschbeck)
Epigenetic Mechanisms of Aging and Longevity (Shelley Berger)
The Past, Present, and Future of Epigenetics (Joe Fernandez, founder of Active Motif)
The Interchromatin Network Model (Ana Pombo)
Dosage Compensation in Drosophila (Asifa Akhtar)
Spatial Organization of the Human Genome (Wendy Bickmore)
Heterochromatin and Phase Separation (Gary Karpen)
Diabetes and Epigenetics (Jean-Sébastien Annicotte)
Epigenetics and X-inactivation (Edith Heard)
Create your
podcast in
minutes
It is Free
DNA Today: A Genetics Podcast
Museum of the Missing
Strange by Nature Podcast
Sasquatch Chronicles
Hidden Brain