Understanding Inherited Cancer Syndromes: Insights and Innovations

Host:  Jennifer Hunter, PhD Assistant Director for Family and Consumer Sciences Extension, University of Kentucky

Guest: Dr. John D'Orazio, Chief of Pediatric Division of Hematology and Oncology at Kentucky Children’s Hospital

This episode of Cancer Conversations on Talking FACS features an in-depth discussion with Dr. John D'Orazio, Chief of Pediatric Division of Hematology and Oncology at Kentucky Children’s Hospital, about the complex topic of inherited cancer syndrome.

Dr. D'Orazio shares his expertise on how genetic mutations can lead to increased cancer risks, particularly in pediatric patients. He explains the concept of inherited cancer syndrome and the types of childhood cancers most likely to be influenced by genetic factors. Discover the role of genetic counselors and the clinical clues that can indicate a potential inherited cancer risk within families.

The episode highlights the innovative approaches being taken at the Markey Cancer Center, including the groundbreaking Project Inherited Cancer Risk, which offers next-gen whole exome sequencing to identify genetic mutations in young cancer patients. Learn about the personalized surveillance plans and specialized clinics, such as the Cancer Predisposition Clinic, that provide ongoing support and monitoring for patients with these genetic predispositions.

Dr. D'Orazio also shares exciting news about the expansion of these services across Kentucky, making them accessible to more families throughout the state.

Cancer Conversations on Talking FACS is a partnership project between Family and Consumer Sciences Extension and the Markey Cancer Center.

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