Human Aspirate - Native Coronary Arteries Versus Vein Grafts

Just two weeks after this podcast was originally recorded, our Editor in Chief Dr. William C. Stanley passed away unexpectedly. We are all tremendously saddened by this loss, but feel that presenting this podcast—the last one recorded with Dr. Stanley—honors his work in the journal, in particular his innovative podcast series. In this podcast Dr. Stanley interviewed author Petra Kleinbongard (University of Essen Medical School) and leading expert William Chilian (Northeast Ohio Medical University) about the work by Kleinbongard and colleagues comparing downstream human coronary aspirate and soluble substances after stent procedures in patients with native coronary arteries and those who had previously undergone revascularization with a saphenous vein graft. Is the potential for microvascular obstruction the same for both sets of patients? Listen as the experts weigh in on this elegant study which examines the pathophysiological consequences of stenting.

Petra Kleinbongard, Theodor Baars, Stefan Moehlenkamp, Philipp Kahlert, Raimund Erbel, Gerd Heusch Aspirate from human stented native coronary arteries vs. saphenous vein grafts: more endothelin but less particulate debris Am J Physiol Heart Circ Physiol, published online October 15, 2013, DOI: 10.1152/ajpheart.00358.2013.