Links:
About This Episode:
The Sydney Diet-Heart Study was a clinical trial conducted in the 1960s and 1970s that aimed to examine the hypothesis that reducing saturated fat intake in the diet would lead to a reduced risk of heart disease.
However, it really only gained attention after a more recent re-analysis by Ramsden et al., which in recent years has been used as supporting evidence for the idea that increased polyunsaturated fat (PUFA), and specifically linoleic acid, in addition to reduced saturated fat intake, can increase heart disease risk.
This was based on the findings that substituting linoleic acid in place of saturated fat increased all-cause, CVD and CHD mortality.
This is of course counter to prevailing consensus and guidelines in this area, which routinely show reduced risk on replacing SFA with PUFA.
Could this trial undermine the common conclusions that replacing saturated fat with polyunsaturated fat decreases heart disease risk?
In this episode Alan and Danny discuss some of the crucial aspects to understand about this study and what it means for what conclusions can be made about the impact of PUFA broadly, and linoleic acid specifically, on our health.
#353: James Hébert, ScD – Dietary Inflammatory Index
#352: Do Diets Even Work in the Long-term? - A Look at Weight Loss Maintenance
#351: Prof. Glenn Gibson - Human Gut Bacteriology, Prebiotics & Probiotics
#350: Peter Olusoga, PhD & Hugh Gilmore – Coaching Burnout: The Research & Applied Psychology
#349: Prof. Naomi Allen – How the UK Biobank is Powering Chronic Disease Research
#348: Omega-3 Supplementation & Heart Disease
#347: Alex Thomas - Advancing the Sports Nutritionist Profession
#346: Kathryn Bradbury, PhD – Diet & Colorectal Cancer Risk
#345: Rebecca Leech, PhD – Impact of Meal Patterning on Diet Quality & Health
#344: Prof. Martin Caraher – Food Poverty & Food Aid Provision
#343: Understanding Causality in Nutrition Science
#342: Are Vegan Diets Superior for Health?
#340: Ethics of Veganism & Omnivorism (Part 4) – Diana Rodgers, RD & Robb Wolf
#339: Prof. Corinna Hawkes - Food Policy, Food Systems & Public Health
#338: Ethics of Veganism & Omnivorism (Part 3) - Alex O' Connor
#337: Ethics of Veganism & Omnivorism (Part 2) – Prof. Paul Thompson
#336: Ethics of Veganism & Omnivorism (Part 1) – Andrew Chignell, PhD
#335: Kyra Bobinet, MD – Systems, Dietary Behaviour Change & the Iterative Mindset
#334: Austin Baraki, MD – Potential Harms of Screening, Overdiagnosis and Overtreatment
#333: Diet & Immunity
Create your
podcast in
minutes
It is Free
Good Mood Revolution
Practically Healthy by Dr. Melina
Intermittent Fasting Stories
ZOE Science & Nutrition
Health Hacks with Mark Hyman, M.D.
Skinquiries