Links:
About This Episode:
The Sydney Diet-Heart Study was a clinical trial conducted in the 1960s and 1970s that aimed to examine the hypothesis that reducing saturated fat intake in the diet would lead to a reduced risk of heart disease.
However, it really only gained attention after a more recent re-analysis by Ramsden et al., which in recent years has been used as supporting evidence for the idea that increased polyunsaturated fat (PUFA), and specifically linoleic acid, in addition to reduced saturated fat intake, can increase heart disease risk.
This was based on the findings that substituting linoleic acid in place of saturated fat increased all-cause, CVD and CHD mortality.
This is of course counter to prevailing consensus and guidelines in this area, which routinely show reduced risk on replacing SFA with PUFA.
Could this trial undermine the common conclusions that replacing saturated fat with polyunsaturated fat decreases heart disease risk?
In this episode Alan and Danny discuss some of the crucial aspects to understand about this study and what it means for what conclusions can be made about the impact of PUFA broadly, and linoleic acid specifically, on our health.
#370: Jake Mey, PhD, RD - Dietetics, Evidence-based Practice & Translating Science into Advice
#369: Prof. Jason Gill - Population Cardiometabolic Disease Risk: Impact of Strength, Fitness & Activity
#368: Shannon Beer – Intentional Eating, Flourishing Health & Behavioural Psychology
#367: Gabrielle Fundaro, PhD – Mindful Eating, Facilitating Health Behaviour Change & Client-centred Coaching
#366: Listener Q&A
#365: David Robert Grimes, PhD – Conspiracy Theories & Bad Information: Why Are We Susceptible?
#364: Jake Linardon, PhD - Disordered Eating: Impact of Macro Tracking & Social Media
#363: Public Health Policy vs. Personal Responsibility: Evidence vs. Ideology
#362: Alistair Monteyne – Impact of Mycoprotein & Vegan Diets on Muscle Protein Synthesis
#361: Sarah Berry, PhD – The PREDICT Study, Postprandial Metabolism & Personalised Nutrition
#360: Nick Hiebert – Micronutrients, Anti-nutrients and Non-essential Nutrients
#359: Calorie Confusion - (Mis)Understanding Energy Balance
#358: Coffee & Health
#357: Nicky Keay, MB BChir – Female Athletes: Hormones, Energy Availability & the Menstrual Cycle
#356: Hana Kahleova, MD, PhD – Plant-based Diets, Meal Timing & Meal Frequency
#355: Is Time-restricted Eating Dead?: A Closer Look
#354: Problems with the Meta-Analysis in Nutrition
#353: James Hébert, ScD – Dietary Inflammatory Index
#352: Do Diets Even Work in the Long-term? - A Look at Weight Loss Maintenance
#351: Prof. Glenn Gibson - Human Gut Bacteriology, Prebiotics & Probiotics
Create your
podcast in
minutes
It is Free
Good Mood Revolution
Practically Healthy by Dr. Melina
ZOE Science & Nutrition
Intermittent Fasting Stories
LONGEVITY with Nathalie Niddam
Nutrition Diva