Question: What cofactors are needed to synthesize and recycle BH4?
Short Answer: Zinc, magnesium, potassium, and niacin are the cofactors needed for the synthesis and recycling of BH4. Folate and methylation are not involved, though high-dose folate or folic acid could hypothetically hurt BH4 recycling since both are recycled by dihydrofolate reductase (DHFR).
This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link:
https://chrismasterjohnphd.substack.com/p/questions-on-vitamin-d-sulfate-synthesis
In that batch of free episodes you will also find the answers to these questions:
Is It Important to Get Vitamin D Sulfate Specifically From the Sun?
How Much Iron Can We Absorb At Once?
If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up:
https://chrismasterjohnphd.substack.com/qanda
Learn more about the Masterpass here:
https://chrismasterjohnphd.substack.com/about
This snippet is from the February 15, 2023 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:
Is It Important to Get Vitamin D Sulfate Specifically From the Sun?
How Much Iron Can We Absorb At Once?
What nutrients are important for long-term PPI use?
For how long does transferrin saturation respond to recent iron-rich food?
Muscle spasms: creatine, creatinine, sodium, and potassium.
Hematologists ignore iron saturation.
How to detox arsenic?
Could folic acid supplements impair BH4 recycling?
How to increase butyrate?
More on hematologists and transferrin saturation.
Here’s a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-february
Dmitry Kats, PhD: From Niatonin to Niacur
Jessica Rose: Adverse Events Reporting and Much More
Patenting the Human Genome With Law Professor Jorge L. Contreras
Tess Lawrie
Stephanie Seneff
Dr. David Brownstein
My Speech at the NYC Nov 20th World Wide Rally for Freedom
How I Lost My COVID Weight
Please Attend the World Wide Rally for Freedom TOMORROW!
FDA Wants Until 2076 to Release Pfizer Data (?!)
New CDC Natural Immunity Study (Long Version)
The New CDC Natural Immunity Study (Short Version)
Natural Immunity
If glutathione whitens your skin, is that good or bad? | Masterjohn Q&A Files #294
Vitamin D supplements, testing, and interactions with the vaccine. | Masterjohn Q&A Files #293
BH4 vs tyrosine for low neurotransmitters and a high phenylalanine-to-tyrosine ratio. | Masterjohn Q&A Files #292
Does TMG have to be taken in the fasting state? | Masterjohn Q&A Files #291
Is urinary mycotoxin testing useful for indoor mold exposure? | Masterjohn Q&A Files #290
Ferritin sky-high without hemochromatosis? | Masterjohn Q&A Files #289
Will the booster shot be worth it? | Masterjohn Q&A Files #288
Create your
podcast in
minutes
It is Free
Good Mood Revolution
Practically Healthy by Dr. Melina
Intermittent Fasting Stories
ZOE Science & Nutrition
Health Hacks with Mark Hyman, M.D.
Skinquiries