In this “Ask Me Anything” (AMA) episode, Peter and Bob discuss all things related to testosterone: what happens when testosterone levels are low, and the potential benefits and risks of testosterone replacement therapy (TRT). They explain the physiology of testosterone, how it works, and how its level changes over the course of a person's life. They have a detailed discussion about existing literature, which reveals vast potential structural, functional, and metabolic benefits of testosterone replacement therapy. They also take a very close look at potential risks of this therapy, with a focus on the controversial effects on cardiovascular disease and prostate cancer.
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We discuss:
#250 ‒ Training principles for longevity | Andy Galpin, Ph.D. (PART II)
#249 ‒ How the brain works, Andrew’s fascinating backstory, improving scientific literacy, and more | Andrew Huberman, Ph.D.
#248 ‒ OUTLIVE book: A behind-the-scenes look into the writing of this book, motivation, main themes, and more
#247 ‒ Preventing cardiovascular disease: the latest in diagnostic imaging, blood pressure, metabolic health, and more | Ethan Weiss, M.D.
#246 - AMA #45: Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent
#245 ‒ Overcoming trauma, finding inner peace, and living a meaningful and fulfilling life | Lewis Howes
#244 ‒ The history of the cell, cell therapy, gene therapy, and more | Siddhartha Mukherjee
#243 ‒ The fentanyl crisis and why everyone should be paying attention | Anthony Hipolito
#242 - AMA #44: Peter’s historical changes in body composition with his evolving dietary, fasting, and training protocols
#241 ‒ Living intentionally, valuing time, prioritizing relationships, and more keys to a rich life | Ric Elias (Part 2)
#240 ‒ The confusion around HDL and its link to cardiovascular disease | Dan Rader, M.D.
#239 ‒ The science of strength, muscle, and training for longevity | Andy Galpin, Ph.D. (PART I)
#238 – AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease
#237 ‒ Optimizing life for maximum fulfillment | Bill Perkins
#236 ‒ Neurodegenerative disease: pathology, screening, and prevention | Kellyann Niotis, M.D.
James Clear: Building & Changing Habits (#183 rebroadcast)
#235 ‒ Training principles for mass and strength, changing views on nutrition, creatine supplementation, and more | Layne Norton, Ph.D.
#234 ‒ Chris Hemsworth on Limitless, longevity, and happiness
#233 - AMA #42: Optimizing sleep - bedtime routine, molecule regimen, sleep trackers, sauna, & more
#232 ‒ Shoulder, elbow, wrist, and hand: diagnosis, treatment, and surgery of the upper extremities | Alton Barron, M.D.
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