In this “Ask Me Anything” (AMA) episode, Peter and Bob discuss all things related to testosterone: what happens when testosterone levels are low, and the potential benefits and risks of testosterone replacement therapy (TRT). They explain the physiology of testosterone, how it works, and how its level changes over the course of a person's life. They have a detailed discussion about existing literature, which reveals vast potential structural, functional, and metabolic benefits of testosterone replacement therapy. They also take a very close look at potential risks of this therapy, with a focus on the controversial effects on cardiovascular disease and prostate cancer.
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We discuss:
#232 ‒ Shoulder, elbow, wrist, and hand: diagnosis, treatment, and surgery of the upper extremities | Alton Barron, M.D.
A masterclass on insulin resistance—mechanisms and implications | Gerald Shulman, M.D., Ph.D. (#140 rebroadcast)
#231 - AMA #41: Medicine 3.0, developments in the field of aging, healthy habits in times of stress, and more
#230 ‒ Cardiovascular disease in women: prevention, risk factors, lipids, and more | Erin Michos, M.D.
#229 ‒ Understanding cardiovascular disease risk, cholesterol, and apoB
#228 ‒ Improving body composition, female-specific training principles, and overcoming an eating disorder | Holly Baxter, APD
#227 - AMA #40: Body composition, protein, time-restricted feeding, fasting, DEXA scans, and more
#226 ‒ The science of happiness | Arthur Brooks, Ph.D.
#225 ‒ The comfort crisis, doing hard things, rucking, and more | Michael Easter, MA
#224 ‒ Dietary protein: amount needed, ideal timing, quality, and more | Don Layman, Ph.D.
#223 - AMA #39: The Centenarian Decathlon, zone 2, VO2 max, and more
#222 ‒ How nutrition impacts longevity | Matt Kaeberlein, Ph.D
#221 ‒ Understanding sleep and how to improve it
#220 ‒ Ketamine: Benefits, risks, and promising therapeutic potential | Celia Morgan, Ph.D.
#219 ‒ Dialectical behavior therapy (DBT): skills for overcoming depression , emotional dysregulation, and more | Shireen Rizvi, Ph.D., ABPP
#218 - AMA #38: Can you exercise too much?
#217 ‒ Exercise, VO2 max, and longevity | Mike Joyner, M.D.
#216 - Metabolomics, NAD+, and cancer metabolism | Josh Rabinowitz, M.D., Ph.D.
#215 - The gut-brain connection | Michael Gershon, M.D.
#214 - AMA #37: Bone health—everything you need to know
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