“Depression is the number one reason in the world for disability,” says Audrey Gruss, Founder of Hopefragrances.com and Hopefordepression.org. “Thirty-five percent of people don’t respond to the meds out there.” Gruss, who began her career as the assistant to the Medical Director at the Revlon Research Center, says that since 1985, every medication has been a spinoff of Prozac, which doesn’t work for everyone. One of those who Prozac failed was her mother, Hope, who had struggled with depression since her thirties. “It was called a nervous breakdown,” Gruss says. “It had stigma.” When visiting her mother at the hospital Gruss would ask why there was no cure and why the top companies in the brain science business were not doing research. The answer she got: research “was too expensive and it was too lucrative to simply repurpose drugs.” After her mother passed away in 2005, Gruss, who had spent the majority of her career in the beauty sector working for name brands like Elizabeth Arden and creating the Doral Saturnia Spa in Miami, launched Hope Fragrances to fund her research foundation, Hope For Depression. “We put together a group of leaders in each discipline of neuroscience and cellular biology,” she says. “They are collaborating and sharing research. We are in clinical trials at Columbia University Medical Center and Mount Sinai with a brand new category of medications for people who don’t respond to Prozac.”
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#209: He Decided to Start a New Business – Every Year! (Sean Castrina)
#208 Taking Her Reinvention Story to the Stage (LeeAnn Marie Webster)
#208 Reinventing Your Relationship to Uncertainty (Jill Griffin)
#207 My Reinvention Took Me from Poverty to the White House (Rebecca Contreras)
#207 From Bartender to Social Media Maven (Stacey Birch)
#205 Reinvent Your Approach to Self Promotion In The Digital Age (Alice Draper)
#204 The Near-Death Experience That Forced My Reinvention (Geralyn Ritter)
#203 When a Health Crisis Becomes a Transformative Journey (Elena Sonnino)
#202 When Your Personal Reinvention Leads to Groundbreaking Change for Autism (Dr. Joan Fallon)
#201 Reinventing Your Mindset About Aging (Judy Katz)
#200 When Your Reinvention Leads You to Run for Political Office (But You Lose) (Claire Campos-O’Neal)
#199 Using Reinvention to Navigate Grief (Katty Douraghy)
#198 Reinventing Your Time Management Skills (Ashley Whillans)
#197 Reinventing Your Career Mindset After Decades in One Industry (Jackie MacDougall)
#196 Walking Away from the Golden Handcuffs that are Literally Killing You (Monica Froese)
#195 Reframing Your Career (After Burnout) to Make it New Again (Stephanie Smirnov)
#194 Reinventing Because You Can’t Walk Away from the Paycheck (Heather Frimmer)
#193 When You Don’t Fit Into the Corporate Box Because You Are Multi-Passionate (Sarabeth Berk)
#192 Ditching the Financial Security of the Legal World to Fight for Women’s Equality (Taina Bien-Aime)
#191 Reaching the Pinnacle of Corporate Success and Walking Away (Traci Schubert Barrett)
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