“Depression is the number one reason in the world for disability,” says Audrey Gruss, Founder of Hopefragrances.com and Hopefordepression.org. “Thirty-five percent of people don’t respond to the meds out there.” Gruss, who began her career as the assistant to the Medical Director at the Revlon Research Center, says that since 1985, every medication has been a spinoff of Prozac, which doesn’t work for everyone. One of those who Prozac failed was her mother, Hope, who had struggled with depression since her thirties. “It was called a nervous breakdown,” Gruss says. “It had stigma.” When visiting her mother at the hospital Gruss would ask why there was no cure and why the top companies in the brain science business were not doing research. The answer she got: research “was too expensive and it was too lucrative to simply repurpose drugs.” After her mother passed away in 2005, Gruss, who had spent the majority of her career in the beauty sector working for name brands like Elizabeth Arden and creating the Doral Saturnia Spa in Miami, launched Hope Fragrances to fund her research foundation, Hope For Depression. “We put together a group of leaders in each discipline of neuroscience and cellular biology,” she says. “They are collaborating and sharing research. We are in clinical trials at Columbia University Medical Center and Mount Sinai with a brand new category of medications for people who don’t respond to Prozac.”
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#169: When an Economic Upheaval Forces You to Reinvent Your Career (Susan Schoenberger)
#168 From Nun to Fortune 500 Founder: How One Woman Overcame Her Fear of Reinvention (Ellen Snee)
#167: Reinventing After 50 to Recover Your Life’s Passion (Jennifer Lewis McKay)
#166: How to Reinvent Your Relationship to Your Children’s Education (Caitlin Meister)
#165: When Job Loss Leads to Understanding Your Own Story (Kate Eckman)
#164: Reinventing Your Sleep During Menopause: Solutions! (Hasti Nazem)
#163: Investing Your Life’s Savings in Your Career Reinvention (Janet Gurwitch)
#162 When a Pandemic Trashes Your Business (Paula Floyd)
#161 When a Literal Explosion Forces You to Rethink Your Professional Identity (Christine Bader)
#160 Science as a Platform for Reinvention (Ariel Garten)
#159: When Career Transformation Leads to Personal Reinvention (Kristine Deer)
#158 Reinventing When Life Makes You a Double Caregiver (Laurie James)
#157 Running Her Side Hustle on One Hour a Day (Nicole Malcolm-Manyara)
#156 Graduating from Smith College at Age 67 (Ann Dowsett Johnston)
#155 Growth is in the Struggle (Jennifer Pate)
#154 Don’t Think of it as a Reinvention, But as a Next Step (Marlene Wallach)
#153 Pay Attention to Your Intuition (Sandy Weiner)
#152 How a City Inspired a Reinvention (Debra Shriver)
#151 When Your Parents Expected a Doctor But You Do Everything Else (Catherine Balsam-Schwaber)
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