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About This Episode:
In 1959 a landmark clinical trial, often referred to as the LA Veterans Study, began with the aim to investigate the effects of replacing dietary saturated fats with polyunsaturated fats, on the progression of atherosclerosis and cardiovascular outcomes.
This was an eight-year clinical trial in 846 domiciled male veterans in the US. The diets between the control and experimental groups differed by saturated fat and polyunsaturated fat (particularly linoleic acid) content, but were similar in calories and total dietary fat.
The findings of the study suggested that replacing saturated fat with polyunsaturated fat was beneficial for reducing heart disease risk. However, the study also reported an unexpected increase in non-cardiac mortality in the intervention group, which raised concerns.
In this episode, we discuss why the LA Veterans Study was such a seminal trial and what we can learn from it.
#293: Jessica Setnick, RD – Orthorexia: Positive vs. Pathological Nutrition
#292: Prof. Alexandra Johnstone, PhD – Appetite Control, Satiety & Diet Interventions
#291: Gab Fundaro, PhD – Gut Microbiome, Bacterial Diversity & the Impact of Diet & Probiotics
#290: Menno Henselmans & Eric Helms, PhD - Diet Breaks, Calorie Cycling & Muscle Retention
#289 Ciaran Fairman, PhD – Exercise Interventions in Cancer Treatment
#288: Ted Ryce: Meditation, Communication & Understanding Behaviours
#287: Gregg Slater - Dietary Fatigue, Nutrition Periodization & the Deficit-Adherence Model
#286: James Morton, PhD - Fuelling Elite Sport: Team Sky, Liverpool FC & Carbohydrate Periodization
#285: What is Health? A Conceptual Framework
#284: Simone Harding – Tackling Negative Body Image & Weight Stigma
#283: Alun Williams, PhD - The Genetics & Science Behind the Historic Caster Semenya/IAAF Case
#282: Louise Burke, PhD - Project Supernova: The Science of Fuelling Elite Athletes
#281: Jake Linardon, PhD – Eating Disorders, Binge Eating & Body Image
#280: Kirsty Elliot-Sale, PhD – Energy Availability, Menstrual Disorders & RED-S
#279: Avrum Bluming, MD & Carol Tavris, PhD – Estrogen, Menopause & Misconceptions About Hormone Replacement
#278: Jackson Peos, PhD – The ICECAP Trial, Intermittent Energy Restriction & the Science of Diet Breaks
#277: Eric Helms, PhD - Non-Quantitative Dieting, Personal Experiments & Optimal Weight Gain for Hypertrophy
#276: Nick Gant, PhD - Neurometabolism: Brain Function, Fatigue & Nutritient Interventions
#275: Kate Solovieva - Psychology, Empathy & Coping Strategies for Better Coaching
#274: James Lindsay, PhD - When Peer-Review Goes Wrong
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