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About This Episode:
In 1959 a landmark clinical trial, often referred to as the LA Veterans Study, began with the aim to investigate the effects of replacing dietary saturated fats with polyunsaturated fats, on the progression of atherosclerosis and cardiovascular outcomes.
This was an eight-year clinical trial in 846 domiciled male veterans in the US. The diets between the control and experimental groups differed by saturated fat and polyunsaturated fat (particularly linoleic acid) content, but were similar in calories and total dietary fat.
The findings of the study suggested that replacing saturated fat with polyunsaturated fat was beneficial for reducing heart disease risk. However, the study also reported an unexpected increase in non-cardiac mortality in the intervention group, which raised concerns.
In this episode, we discuss why the LA Veterans Study was such a seminal trial and what we can learn from it.
#370: Jake Mey, PhD, RD - Dietetics, Evidence-based Practice & Translating Science into Advice
#369: Prof. Jason Gill - Population Cardiometabolic Disease Risk: Impact of Strength, Fitness & Activity
#368: Shannon Beer – Intentional Eating, Flourishing Health & Behavioural Psychology
#367: Gabrielle Fundaro, PhD – Mindful Eating, Facilitating Health Behaviour Change & Client-centred Coaching
#366: Listener Q&A
#365: David Robert Grimes, PhD – Conspiracy Theories & Bad Information: Why Are We Susceptible?
#364: Jake Linardon, PhD - Disordered Eating: Impact of Macro Tracking & Social Media
#363: Public Health Policy vs. Personal Responsibility: Evidence vs. Ideology
#362: Alistair Monteyne – Impact of Mycoprotein & Vegan Diets on Muscle Protein Synthesis
#361: Sarah Berry, PhD – The PREDICT Study, Postprandial Metabolism & Personalised Nutrition
#360: Nick Hiebert – Micronutrients, Anti-nutrients and Non-essential Nutrients
#359: Calorie Confusion - (Mis)Understanding Energy Balance
#358: Coffee & Health
#357: Nicky Keay, MB BChir – Female Athletes: Hormones, Energy Availability & the Menstrual Cycle
#356: Hana Kahleova, MD, PhD – Plant-based Diets, Meal Timing & Meal Frequency
#355: Is Time-restricted Eating Dead?: A Closer Look
#354: Problems with the Meta-Analysis in Nutrition
#353: James Hébert, ScD – Dietary Inflammatory Index
#352: Do Diets Even Work in the Long-term? - A Look at Weight Loss Maintenance
#351: Prof. Glenn Gibson - Human Gut Bacteriology, Prebiotics & Probiotics
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