This is a Premium-exclusive episode, so here you'll only hear a preview. In order to listen to the full episode you’ll need to subscribe to Sigma Nutrition Premium.
About This Episode:
It has been clearly demonstrated that elevated LDL-cholesterol (LDL-C), or perhaps more specifically pro-atherogenic lipoproteins, is causal in atherosclerosis development in humans.
One crucial concept within this is that the risk relates not only to the magnitude of elevated LDL-C, but the duration of exposure. Thus, the role of LDL-C in driving atherosclerosis is referred to as a “cumulative, integrated exposure over the lifecourse”.
But, what exactly does this mean?
In this episode, Danny discusses the cumulative exposure model of LDL-C in atherosclerosis, the evidence supporting it, and the implications of this for the “debates” that get raised in relation to LDL-C (or apoB-containing lipoproteins) and heart disease.
Links:
SNP11: The Death of Domain Expertise
#460: Dr. Priya Sumithran – Body Fat Regulation, Pros & Cons of Weight Loss Interventions, and GLP-1 Receptor Agonists
#459: Nicky Keay, MB BChir – Hormones & Healthspan: The Endocrine System Across the Life Course
What Are Stable Isotopes? How Are Tracers Used in Nutrition Research? (Preview)
#458: How Foods Impact Satiety, Hunger & Appetite
#457: Austin Robinson, PhD – Salt Sensitive vs Salt Resistant, Impacts of Sodium on Health, & Racial Differences in Risk
#456: Prof. Glenn McConell – Glucose Uptake During Exercise & Muscle Insulin Sensitivity
#455: Jill Joyce, PhD – Improving the Diets of Tactical Populations
SNP9: AMA – Blood Pressure, LDL Lowering, PCOS & More!
#454: Eric Helms, PhD – Plant or Animal Protein: Rethinking Protein & Muscle
#453: Nick Gant, PhD – Cognitive Performance: Impact of Caffeine, Nicotine & Creatine (Rebroadcast)
#452: Stuart Phillips, PhD - Bacterially Synthesized Whey, Plant vs. Animal Proteins, Muscle & Extended Fasts, & Much More
#451: Potassium & Blood Pressure: Influence of Sex & Sodium
#450: Megan Rossi, PhD, RD – Diet For a Healthy Gut: Diversity, Fiber Types & Gut Health Pseudoscience
#449: Do Artificial Sweeteners Increase Cancer Risk? (Study Analysis)
#448: Prof. Norman Temple – Can Science Answer Diet-Health Questions?
#447: Does Eating Fish Increase Skin Cancer Risk? Study Analysis
SNP7: Stephan Guyenet, PhD - Ask Me Anything!
#446: How Climate Change Impacts Nutrient Status
#445: Dr. Hazel Wallace - Nutrition for Women’s Health
Create your
podcast in
minutes
It is Free
Good Mood Revolution
Practically Healthy by Dr. Melina
ZOE Science & Nutrition
Intermittent Fasting Stories
LONGEVITY with Nathalie Niddam
Nutrition Diva