Links:
About This Episode:
PREDIMED (Prevención con Dieta Mediterránea) is a landmark clinical trial conducted in Spain.
The study made a huge splash due to the rarity in nutrition of having large RCTs with hard endpoints. In addition, it had results of a large magnitude; showing a 30% reduction in cardiovascular events.
But the study did face criticisms and controversies over methodological issues, including randomization procedures at certain centers, ultimately leading to a retraction of the original paper and a re-analysis.
Participants in the PREDIMED trial were randomly assigned to one of three groups:
Despite the issues it still ends up being an incredibly useful source of data.
In this episode we discuss the findings from PREDIMED, some of the potential limitations, and where it sits among the wider Mediterranean Diet literature.
Note: This is a Premium-exclusive episode, so in order to listen to the full episode you’ll need to subscribe to Sigma Nutrition Premium.
#476: Fructose in Perspective – Dietary Villain or Misunderstood Nutrient?
#475: Is Food Addiction Real? – Charlotte Hardman, PhD
SNP15: AMA – Semaglutide, “Carni-nutrients”, Sweating From Caffeine, & More
#474: Glucose Peaks & Variability – Is Lower Better?
#473: Diet & Depression (What Do We Actually Know?) – Nicole Lippman-Barile, PhD
#472: Compared To What? – Understanding Food Substitution Analysis & Adjustment Models
#471: Salt & Bone Health – Is There Cause For Concern?
SNP14: Nutrition Coaching Roundtable (Helms, Huschtscha & Baker)
#470: Melatonin, Meal Timing & Glucose Tolerance
#469: Chrononutrition – New Findings & Updated Views
#468: High Sugar Intakes Without Excess Calories: Harmful or Benign?
SNP13: Intuitive Eating Debate – with Jackson Peos, PhD
#467: Iron Issues in Athletes – Prof. Pete Peeling
#466: Iron Absorption from Foods & Supplements – Prof. Paul Sharp
#465: Diagnosing & Treating Iron Deficiency & Excess – Austin Baraki, MD
#464: Do Sugar Taxes Work?: Evidence on Potential Policies - Kathryn Backholer, PhD
SNP12: The Big Breakfast Study
#463: Do Vegan Diets Cause Depression?
#462: Gyorgy Scrinis, PhD – Ultra-Processed Foods, Nutritionism and Current Food Systems
#461: Prof. Emma Boyland – How Food Marketing Impacts Eating Behaviour
Create your
podcast in
minutes
It is Free
Good Mood Revolution
Practically Healthy by Dr. Melina
ZOE Science & Nutrition
Intermittent Fasting Stories
LONGEVITY with Nathalie Niddam
Nutrition Diva